The structure of DNA & RNA Flashcards
Mononucleotide
DNA belongs to a group of macromolecules
The building blocks of nucleic acids are called mononucleotides
Two principal types nucleic acid are found in cells deoxyribonucleic acid (DNA) ribonucleic acid (RNA)
Mononucletoide
A mononulceotide is made up of
An inorganic phosphate group
A pentose sugar - ribose in RNA & deoxyribose in DNA
A base which contains nitrogen - adenine, guanine, cytosine, uracil (only in RNA) & thymine (only in DNA)
Mononucleotide: two kinds of bases in DNA
Purines
Pyrimidines
Purines
Are double ring bases
Pyrimidines
Are single base rings
Examples: purines
Adenine
Guanine
Examples: pyrimidines
Thymine
Cytosine
Mononucleotide
Condensation reactions join up the inorganic phosphate group & nitrogenous bass to the sugar by removal of water molecules
Formation of dinonucletide
Two monosaccharides removal of water forms dinonucleotide
Nucleotides linked together by condensation reaction forms: bond
Phosphodiester bonds
Formation of polynucleotide
Nucleotides linked together by condensation reaction forms phosphodiester bonds
Polynucleotide
Ribonucleic acids (RNA)
Deoxyribonucleic acids (DNA)
Deoxyribonucleic acid (DNA): single strand
The backbone of the molecule if alternating phosphate & deoxyribose sugar
Pointing inwards from the 2 sugar-phosphate back bones are the bases which makes pairs in a specific way
Deoxyribonucleic acid (DNA): double strand
Remember DNA has two strands that fit together something like a zipper
The two strands which are anti parallel one strand runs from 3’ to 5’ end and the other runs from 5’ to 3’ end
Hydrogen bonds
The bases attract each other because of hydrogens bonds
When making hydrogen bonds
Cytosine always pairs up with guanine
Adenine always pairs up with thymine
Ribonucelic acid (RNA)
RNA is a single polynucleotide chain. The mononucleotides are linked to each other by phospho-diester bonds
RNA can fold into complex shape held in place by hydrogen bonds or remain as long as long thread like molecules
Ribonucleic acid (RNA)
Each mononucleotide contains
A ribose sugar
A nitrogen base (except thymine)
A phosphate group
polymer
RNA