The resting membrane potential Flashcards
Describe Neurons
principle building blocks and instrument for communication in the brain
What are the type of communication within a neuron
chemical synapses
electrical synapses
Describe chemical signals location
dendrite, cell body and axons
Describe electrical signals location
synapses
Describe Neurons cytosol
its potential is 50-70Mv lower than the potential of the extracellular fluid
What does the difference in negative charge cause
Due to the cell being more negative within the cell (50mv-70mv) compared tot he extracellular cytoplasm
this results in a
SEPARATION OF CHARGE
What is the potential of the outside of the cell
Zero
what is the resting membrane caused by
unequal concentration of NA and K
unequal permeability of the cell membrane
small amount due to the electrogenic action of the NA K Pump
what is the approximate concentration of K+ and NA outside of the cell
5mM - K
150mM- NA
what is the approximate concentration of K+ and Na inside of the cell
100mM- K
15mM- NA
what are the two type of channels responsible for unequal permeability of the cell membrane
Non gated channels- open at rest
gated channels- closed at rest
Describe how what kind of channels there are within the cell membrane
more K+ leaky channels but very few leak Na channels
what is the E NA value?
60 mv
Describe the Equilibrium potential
an intracellular potential at which the net flow of ions is zero in spite of a conc gradient and permeability
Describe glia cells resting membrane potential
Glia cells have only leak channels for K+
= -80 mV
