Action potentials: generation and transmission Flashcards

1
Q

What causes the potential inside a cell to change

A

a cells potential is not constant.

it changes its permeability or ion conc changes

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2
Q

What is hyperpolarisation

A

cell becomes more negative -70 to -75.

Potential within the cell moves closer to Ek and Ena

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3
Q

What is depolarisation

A

cell is less negative
-70 to 60.

potential inside the cell moves away from Ek and closer to Ena

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4
Q

When do action potentials occur

A

occurs when voltage reaches a threshold (-55)

occurs due to a short opening of the voltage gated ion channels

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5
Q

What is stage 1-2 in action potentials

A

absolute refractory period

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6
Q

what is stage 3 in action potential

A

relative refractory period

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7
Q

What is the first stage in action potentials

A

a slow depolarization due to stimulus

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8
Q

what is the second stage in action potential

A

after threshold is reached fast depolarization occurs

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9
Q

what is the third stage in action potential

A

repolarization

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10
Q

what is the fourth stage of action potentials

A

after hyperpolarisation

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11
Q

Describe stage 2: Fast deploarisation: action potential mechanisms

A

once threshold is met their is a sudden activation of voltage gated Na ion channels

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12
Q

Describe stage 3 replarisation: action potential mechnisms

A

inactivation of Na ions and activation of K= channels

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13
Q

What causes the Na channel to slow down and stop

A

increase in Na ion causes the inside to become more positive

Na attraction is less

Na channels inactivate

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14
Q

Describe the amplitude of action potentials

A

usually constant

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15
Q

What kind of energy is generated when the current is generate outside of the source

(outside to inside)

A

Hyperpolarisation

MP becomes more negative

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16
Q

What kind of energy is generated when the current is generated inside of the source

(inside to outside)

A

depolarisation

MP becomes less negative

17
Q

Where is the first AP potential generated within the CNS neuron

A

axon hillock which has the lowest threshold

18
Q

What evokes depolarisation within the CNS neuron

A

excitatory postsynaptic potential which spread passvely from the dendrites

19
Q

How do AP travel within the CNS neuron once generated

A

actively along the axon away from the cell body