Review LECT Cells and Tissue Flashcards
Describe Tight junctions
Polar, content occludin
Describe Adheren
Transmembrane cadherin links via catenin to microfilaments actin- cytoplasm
Describe Gap junctions
Content connexin
Describe Desmosome
Cadherin links to Keratin (intermediate filament)
Hemidesmosomes
Integrin bind to Laminin in the BM and Keratin intermediate filament in cytoplasm
What is the Basement Membrane comprised of
Two parts: Basal Lamina and the Reticular lamina
describe the basal Lamina
Secreted by the epithelial cells. Contains collagen, Laminin
Describe reticular Lamina
Produced by fibroblasts contains proteins like fibronectin and collagen
Where is the BM found
between the epithelium and CT
Stratified Columnar Epithelium function and apparearance
Even layering of columnar cells
Protection and secretion
n
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Stratified Cuboidal Epithlium function
Protection secretion and absorption
Stratified Cuboidal Epithlium location
Ducts of sweat glands, Part of the male urethra
Transitional Epithelium appearance
Looks like Stratified cuboidal epithelium when relaxed the outer layer large and rounded scallop shaped.
- stretched outer layer becomes flat and squamous like
Transitional Epithelium location
bladder
Simple Squamous is located where
Endothelium
Lung alveoli, lumen of blood, kidney
Does Stratified epithelia have cilia
No it does not
Describe the appearance of Pseudostratified Columnar epithelium
Goblet cells and taller cells present
Pseudostratisfied as it has no even layer of cells but are all connected to BM
either ciliated or non ciliated
Pseudostratified Columnar epithelium ciliated
location
Trachea
upper respiratory tract
Example and function of Pseudostratified Columnar epithelium ciliated
Upper respiratory tract
secrete mucus and move it
Example and function of Pseudostratified Columnar epithelium non- ciliated
Larger ducts of glands, epididymis, part of male urethra
Absorption and protection
Describe the Glomerulus Structure
HAs a outer layer of Simple Squamous cells and inner area of Bowman capsule
Simple Cuboidal EPI
Pancreas ducts
Simple columnar Non ciliated
Gastrointestinal tract from stomach to anus
Simple columnar ciliated
Parts of upper respiratory tract
Stratified Squamous Keratinised
SKIn
Stratified Squamous non- Keratinised
mouth tongue and oesophagus anus and Vagina
Describe Glandular Epithelia
Single cells that secrete substances into ducts, surfaces or in blood
Endocrine gland
Secretes directly into blood via interstitial fluid
eg: pituitary, Thyroid
Exocrine gland
Secretes into ducts that empty onto the surface of a covering or lining epithelium.
eg sweat and salivary glands
What is the ECM composed of
Ground substance and Protein fibres
Where are the Protein fibres of the ECM and what does the ECM dictate
What is CT made of
ECM and cells
WHat is ground substance made of
water, protiens, polyssacarides (sugar)
polyssacarides (sugar) example and what do they form when joined with core proteins
Glycosaminoglycans.
GAGS join with core proteins to form proteoglycans
Whats are the three major fibres found in ECM
Collagen
Reticular
Elastic
Describe collagen fibres in the ECM
Thick
Describe Reticular fibres in the ECM
Thinner mainly composed of collagen spreads through tissue
Describe Elastic fibres in the ECM
Thin consist of elatic surrounded by fibrillin
3 types of Mature connective tissue
connective tissue proper- adipose
Fluid CT- blood
Supporting CT- Cartilage and bone
DEscribe Erythrocytes
Transport O2 and CO2
Describe Leukocytes
combat disease
Describe Neutrophils and monocytes
phagocytic engulf bacteria
Basophils and Mast cells function
intensify the inflammatory reaction
Eosinophils work against?
Parasite worms and acute allergic response
Lymphocytes are involved in
Immune response
Describe the structure of muscle
Epimysium _around muscle Perumysium- around fascicles Endomysium- around mucle cell Sarcolemma -PM Sarcoplasm- cell cytoplasm
what causes striation within the myofibril
thick and thin filaments
describe smooth muscle
non straited- no sarcomeres
thin filaments “dense bodies’
Intermediate filaments (non contract element also connect to dense bodies
describe smooth muscle contraction
intermediate dont contract. cells twists
What do Astrocytes maintain
Blood brain barrier
Describe Oligodendrocytes
From myelin sheath around CNS axons
Myelination means action potential is faster
Microglia
Function are phagocytic resident macrophage
Ependymal cell
Produce CSF line the ventricles in the brains and central canal they have cilia and microvilli
Peripheral Nervous System Neuroglia features
Schwann cells- myelin and non myelinated axons
Satelite cells- surround the cell bodies. Support fluid exchange
