The hypothalamus and autonomic control Flashcards

1
Q

What is a vital parameter?

A

Anything that when changed and disturbed causes disfunction

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2
Q

Where are contextual inputs integrated in during homeostasis?

A

Into the hypothalamus

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3
Q

What is a contextual input?

A

Cortical areas which feed in on top of sensory inputs

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4
Q

Where does the paraventricular nucleus feed into?

A

ANS
Neuroendocrine

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5
Q

Describe adenohypophysis

A

Troph cells stimulated by releasing hormones from parvocellular neurons of the hypothalamus

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6
Q

Describe neurohypophysis

A

Releases hormones from the magnocellular neurons directly into systemic circulation

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7
Q

Describe the portal system

A

Blood goes from one tissue to the other without returning to the heart or the lungs

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8
Q

What is the cascade following hormone release by parvocellular neuron?

A

Hormone is released ->
Travels into circulatory via portal vein ->
Blood is deoxygenated (doesn’t return to the heart) and carries the hormone to bind to receptors in troph cells ->
These release another hormone and travel in systemic circulation in the body

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9
Q

Describe the release of hormones from the magnocellular neurons

A

Axons go through the pituitary and directly release neurons into the systemic circulation

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10
Q

Define a trophic hormone?

A

A hormone that releases a stimulating effect on other hormones

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11
Q

Where are trophic hormones found?

A

The anterior lobe of the pituitary

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12
Q

Name 3 trophic hormones

A

TSH
FSH + LH
ACTH

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13
Q

Is the ANS involuntary or voluntary?

A

Involuntary

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14
Q

What are the 2 efferent pathways of the ANS?

A

Sympathetic
Parasympathetic

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15
Q

What are the ANS effectors?

A

Smooth muscle
Cardiac muscle
Glands

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16
Q

Which efferent pathway has the nickname fight or flight?

A

Sympathetic nervous system

17
Q

Which efferent pathway has the nickname rest and digest?

A

Parasympathetic nervous system

18
Q

Where do the sympathetic neurons come from?

A

Thoracic
Lumbar

19
Q

Where do the parasympathetic neurons come from?

A

Sacral spinal cord
Brain

20
Q

How does the ANS function without the hypothalamus?

A

Sensory afferent division ->
Brainstem nuclei ->
Motor efferent division

  • The degree of hypothalamic control depends on the parameter
21
Q

What is the organisation of the sympathetic ns?

A

Cervical spinal cord
Thoracic
Lumbar
Sacral

22
Q

What information is processed in the dorsal horn?

A

Sensory info

23
Q

What information is processed in the ventral horn?

A

Motor info

24
Q

What neurons are in intermediolateral cell column?

A

Preganglionic sympathetic neurons

25
Q

Where do sympathetic neurons join the sympathetic chain ganglion?

A

Higher than T1 and L3

26
Q

Where do neurons for the sacral parasympathetic organisation come from?

A

Intermediate via ventral root to ganglia near the target organ

27
Q

What neurotransmitter does the sacral parasympathetic organisation use? What receptor does this activate?

A

Acetylcholine
Muscarinic acetylcholine receptor

28
Q

What nerve controls pupil dilation?

A

Oculomotor nerve

29
Q

What is cranial nerve 3?

A

Oculomotor nerve

30
Q

What is cranial nerve 10?

A

Vagus nerve