The Gut as an Immune Organ Flashcards
1
Q
How many layers of epithelium separate the gut lumen from the tissues?
A
One
2
Q
Where is the majority of the body’s immune system contained?
A
Gut
3
Q
Which is the secretory immunoglobulin?
A
IgA
4
Q
What does the gut secrete into the gut lumen when absorbing nutrients?
A
IgA antibodies
5
Q
What is the consequence of an absence of T cells in the gut?
A
chronic low-grade infections
6
Q
Where are mucosal protective immune responses generated and expressed in the small intestine (ileum specifically)?
A
Responses generated in Peyer’s patches and are expressed in the lamina propria