Gastric Acid Secretion and its Prevention

Question 1

Name the different contributions to body fluid

Answer 1

saliva, gastric juice, pancreatic juice, bile, intestinal juice

Question 2

What is the function of lysozyme?

Answer 2

destroys bacterial membranes

Question 3

What is the function of growth factors?

Answer 3

stimulate epithelial proliferation which is particularly protective for the oesophageal epithelium which is subject to abrasion

Question 4

Where is mucus secreted in the stomach?

Answer 4

By mucous cells over the entire luminal surface which extend down into glands as mucous neck cells which secrete bicarbonate-rich mucus to coat and lubricate the gastric surface to protect the epithelium

Question 5

Where is acid secreted in the stomach?

Answer 5

by parietal cells (secrete HCl) which activates pepsinogen and inactivates any ingested microorganisms

Question 6

Where are proteases secreted in the stomach?

Answer 6

pepsinogen is secreted by chief cells which is activated by a low pH to pepsin

Question 7

What is the role of lipase?

Answer 7

initiates triglyceride digestion

Question 8

What is the role of intrinsic factor?

Answer 8

glycoproteins from parietal and chief cells bind vitamin B12 in the intestine in order to facilitate absorption

Question 9

What’s the most common cause of peptic ulcer?

Answer 9

Helicobacter pylori which is treated with combination of 2 different types of antibiotic and a protein pump inhibitor

Question 10

What’s the second most common cause of peptic ulcer?

Answer 10

NSAIDS