The GIT Nutrition Flashcards

1
Q

Nutrition

A

-The process of obtaining or providing food for good health
-Science that deals with nutrients and nutrition

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2
Q

What are the four categories of undernutrition?

A
  1. Wasting(low weight for height)
  2. Stunting(low height for age)
  3. Underweight(low weight for age)
  4. Vitamin and mineral deficiency
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3
Q

Wasting?

A

Usually indicates recent & severe weight loss,
* Due to insufficient food to eat and/or infectious disease e.g. diarrhoea

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4
Q

Stunting?

A
  • Result of chronic or recurrent undernutrition
  • Usually associated with poor socioeconomic conditions, poor maternal health & nutrition,
    frequent illness, and/or inappropriate infant and young child feeding and care in early life.
  • Affects cognitive function
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5
Q

Underweight?

A

A child who is underweight may be stunted, wasted, or both

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6
Q

Vitamin and mineral deficiency(inadequate micronutrient intake)

A

Children & pregnant women in low income countries particularly at
risk of developing deficiencies in
* vitamin A
* Iodine
* Iron

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7
Q

Overweight and obesity?

A
  • Person too heavy for his or her height
  • Risk factor for cardiometabolic diseases
  • Imbalance between energy consumption (too much) vs energy expended (too little)
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8
Q

Hidden hunger?

A

Presence of multiple micronutrient deficiencies
-Particularly iron, zinc, iodine and vitamin A
-Can occur without a deficit in energy intake
-Energy-dense, but nutrient-poor diet.

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9
Q

How many people are affected by hidden?

A

Affects > 2 billion people globally
-particularly in low- and middle-income countries

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10
Q

What causes hidden hunger?

A

Due to reliance on low-cost food staples & non diverse diet

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11
Q

Double burden of malnutrition?

A

Coexistence of undernutrition & overweight, obesity or diet-related

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12
Q

How does the double burden of malnutrition occur?

A

i. Within individuals -simultaneous presence of two or more types of
malnutrition, or multiple types over a lifetime (obese & deficient in
micronutrients)

ii. Households -different family members presenting with different types of
malnutrition (under and over nutrition)

iii. Populations/Communities/countries (usually due to socioeconomic factors), and across the life-course

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13
Q

What are the three assessments of nutrtional status?

A
  1. Clinical Knowledge
  2. Biochemical tests: blood/serum & tissue biopsies(urine, saliva and hair)
  3. Anthropometry
  4. Dietary Survey
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14
Q

Bioimpedience?

A

is about the electrical properties of your body or other biomaterials

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15
Q

Anthropometry?

A

-Skin fold thickness measurements
-Waist circumference determination
-Height
-Weight
-Body mass index computation (kg/m²)
-A BMI of 25.0 to <30.0 is denotes overweight while a BMI >30.0 denotes obesity
-Arm circumference
-Head circumference

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16
Q

Dietary survey?

A

For this direct records of individuals diets are taken and inferences drawn
based on the nutrient composition of the dietary constituents

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17
Q

What are the dietary survey methods?

A
  1. Prospective Methods
  2. Retrospective Methods
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18
Q

Prospective Methods?

A

7 day food record or 72 hour record of nutrient
intake
-keeps diary & record all foods and beverages
consumed during the specified time period.
-The quantity of each component is also recorded

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19
Q

Retrospective Methods?

A

Dietary intake recall
-Either as a food frequency (per
day/week/month) or 24 hour recall. Further
details will be provided in the lab sessio

20
Q

Limitations of methods especially recall (retrospective)

A

over/under estimation of food consumption

21
Q

What are the quality control measures that are instituted?

A

i. Crosschecking. Use more than 1 method (e.g. 24h recall and food frequency) to avoid over/under
reporting.
ii. Validation. Check how a method actually assessed intake.
iii. Reliability. Check consistency of data.

22
Q

Proximate analysis?

A

Determination of the macronutrients in food

23
Q

What is trans fat?

A

Trans fat, also called trans-unsaturated fatty acids, or trans fatty acids, is a type of unsaturated fat that occurs in foods.

24
Q

 RDI vs RDA vs DV

A

RDI (Reference Daily Intake) is a population-adjusted RDA based on all ages and sex groups of RDA values.

Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97–98%) healthy individuals; often used to plan nutritionally adequate diets for individuals.

The Daily Value (DV) is put on the labels of food products and is meant for the general population.

25
Instrument used to measure energy?
Bomb calorimeter often used to determine the energy content of food constituents
26
Digestibility?
Digestibility: quantification of the digestive process provides a relative measure of the extent to which ingested food and its constituent nutrients have been digested and absorbed
27
What happens to all undigested food?
Thus, only a portion of food is digested and absorbed by an individual * The rest is excreted as faeces
28
What are the factors affecting digestibility?
1. Food composition 2. Host factors -GIT anatomy -GIT microbiome -Age 3. Food characteristics -Cooking -ANFs
29
Determination of digestibility?
1. In vivo methods 2. In vitro methods
30
In Vivo methods?
1. Direct/Conventional approach 2. Indirect method/Indifference method or indicators/markers method
31
Direct/Conventional approach?
Determine feed or nutrient intake and faecal production
32
Nutrient digestibility equation?
Nutrient Digestibility= [(𝑛𝑢𝑡𝑟𝑖𝑒𝑛𝑡 𝑎𝑚𝑜𝑢𝑛𝑡 𝑖𝑛 𝑓𝑒𝑒𝑑 𝑐𝑜𝑛𝑠𝑢𝑚𝑒𝑑 − 𝑛𝑢𝑡𝑟𝑖𝑒𝑛𝑡 𝑎𝑚𝑜𝑢𝑛𝑡 𝑖𝑛 𝑓𝑎𝑒𝑐𝑒𝑠)/ 𝑎𝑚𝑜𝑢𝑛𝑡 𝑛𝑢𝑡𝑟𝑖𝑒𝑛𝑡 𝑖𝑛 𝑓𝑒𝑒𝑑 𝑐𝑜𝑛𝑠𝑢𝑚𝑒𝑑] x 100
33
Apparent digestibility coefficients?
when faecal samples are collected
34
Apparent digestibility coefficients factors?
1. Feces contain added components from the GIT (mucosal cells, secretions) & microbes. 2. Microbial fermentation can also have an impact
35
True digestibility coefficient?
requires collection of samples from the ileum
36
In Vitro methods?
Use simulated process in the gastrointestinal tract
37
Which animals are of choice for digestibility trails?
Often rat and pig are animals of choice for digestibility trials
38
What is the direct method for experimental animal models for digestibility?
Use metabolic cage -Feed known amount of feed -Collect faecal matter separately from urine -Proximate analysis of feed and faeces -Compute apparent digestibility coefficients Nb for Crude protein determine N and multiple by 6.25
39
Which samples are collected for true digestibility?
For true digestibility, ileal samples are collected
40
How does the rat GIT differ from the pig and both vs the human?
Pigs and rats have a digestive system which is classified as monogastric, or nonruminant. Humans also have this type of digestive system. They have one stomach (mono = one, gastric = stomach). The monogastric differs from that of a polygastric, or ruminant, digestive system found in cattle and sheep.
41
Antinutritional factors (ANF)?
1. Chemical substances present in food 2. Alter the digestion and absorption of Nutrients 3. Reduce the bioavailabity of food constituents 4.Cause nutritional deficiencies, poor growth and diseases
42
Mechanisms of action Digestive enzyme inhibition?
 1. Inactivation of nutrients  2. Alteration of nutrient absorption pathways  3. Direct/indirect effects on tissues once absorbed
43
Phytochemicals?
Plant-derived chemicals
44
Nutraceuticals?
phytochemicals with nutritional value and medicinal potential
45
Effects of cooking food?
-Improve digestibility of some macronutrients -Decrease availability of some micronutrients
46
Effects of advanced glycation end products?
-Flavour -↓Digestibility -Carcinogens -Chronic disease -Ageing