The Eye in Health and Disease Flashcards

1
Q

What are the basic components of the eye?

A

bony orbit, contents, eyeball, eyelids, lacrimal apparatus, muscles

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2
Q

What is the ‘tear-drop sign’ indicative of?

A

An orbital floor fracture which has herniated into the maxillary sinus

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3
Q

What is the role of orbital fat?

A

Cushioning the globe. Key for support

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4
Q

What components make up the outer fibrous coat of the eye?

A

The sclera and cornea

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5
Q

What components make up to middle vascular coat of the eye?

A

The iris, ciliary body, choroid

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6
Q

What makes up the outer sensory coat of the eye?

A

Retina

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7
Q

What liquid like substance resides in the anterior portion of the eye?

A

Aqueous humour

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8
Q

What gel like substance is contained in the posterior portion of the eye?

A

Vitreous humour

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9
Q

Describe the cornea

A

The anterior 1/6 of the fibrous outer coat, transparent window that will allow light rays to enter the eyeball

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10
Q

Describe the sclera

A

The posterior 5/6 of the fibrous outer coat, gives attachment to the muscles moving the eyeball

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11
Q

Describe the histology of the cornea

A

Stratified squamous non-keritanized epithelium

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12
Q

What is Bowman’s membrane?

A

The basement membrane of the corneal epithelium

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13
Q

What are the stroma of the corneal epithelium?

A

Regularly arranged collagen deposits with no blood vessels

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14
Q

What are the three factors which maintain the transparency of the cornea?

A

Histologically - regular arrangement of collagen in the stroma
No blood vessels
Endothelium cell layer has a pump that actively keeps the aqueous humour out

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15
Q

What are the two categories of corneal pathology?

A

Inflammatory - e.g. corneal ulcers

Non-inflammatory - e.g. dystrophies

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16
Q

What is a common result of corneal pathology?

A

Opacification. May need to be treated by corneal transplant - Keratoplasty

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17
Q

Why is avascularity important to surgeons performing a corneal graft?

A

The lack of blood supply results in a lesser chance of foreign antigens from a donor graft being detected by the host immune system and therefore less chance of subsequent rejection. Cornea is “immune-privileged’

18
Q

Describe the function of the iris

A

Controls the diameter of the pupils and therefore the amount of light rays entering the eyeball

19
Q

Describe the function of the ciliary body

A

Suspends the lens and produces Aqueous Humour

20
Q

Describe the function of the choroid

A

Supplies the blood to the outer layers of the retina

21
Q

What are the key histological layers of the retina?

A

9, the nerve fibre layer
2, the layer of rods and cones
1, the pigment epithelial layer

22
Q

What are the four quadrants of the retina?

A

Clockwise from top-left of the left eye; superonasal, superotemporal, inferotemporal, inferonasal

23
Q

What is the optic disc?

A

The start of the optic nerve, a physiological blind spot

24
Q

What is the fovea centralis?

A

A small, central pit composed of closely packed cones in the eye. It is located in the center of the retina. The high number of cones gives high visual acuity

25
Q

Describe the lens

A

A transparent, crystalline biconvex structure which is suspended by zones from the ciliary body. It can change shape

26
Q

What feature allows the lens to be transparent?

A

Avascularity

27
Q

What is another name for lens opacification?

A

Cataract

28
Q

What is a function of aqueous humour?

A

To maintain intraocular pressure

29
Q

What is a function of vitreous humour?

A

To cushion the retina

30
Q

Where is aqueous humour produced?

A

By the ciliary body, in the posterior chamber - the space behind the iris and in front of the lens

31
Q

What can an obstruction along the pathway of aqueous humour cause?

A

Damming up of AH and therefore increased intraocular pressure i.e. Glaucoma

32
Q

Describe the conjunctiva

A

Thin vascular membranes that cover the the inner surface of eyelids and loop back over the sclera. It does not cover the cornea

33
Q

What are the two conjunctiva?

A

Bulbar - over the sclera

Palpebral - covering the innner surface of the eyelid

34
Q

Where is the lacrimal gland situated?

A

Laterally in the orbit

35
Q

How do tears reach the surface of the eye?

A

Through punctae on the medial side if each eyelid

36
Q

Where do tears drain to from the eyelid?

A

The lacrimal sac which sits over the lacrimal bone, then draining through the nasolacrimal duct into the inferior meatus of the nasal cavity

37
Q

What are the four functions of the tear film?

A

Keeps the cornea moist
Washes away particulate foreign bodies
Contains antibodies and lysosomes to kill microbes
Smooths outer surface the cornea providing smooth surface for refraction

38
Q

What dye can be used to visualise the tear film?

A

Fluorescein

39
Q

Describe the first (deepest) layer of the tear film

A

Mucinous layer which makes up around 30% of the tear film. Overlies the corneal epithelium

40
Q

Describe the second (middle) layer of the tear film

A

The aqueous layer which makes up around 69% of the film. Overlies the mucinous layer

41
Q

Describe the third (superficial) layer of the tear film

A

The oily layer (~1%)

42
Q

How is aqueous humour filtered out of the anterior portion of the eye?

A

When it reaches the angle of the AC it is filtered out through a meshwork called the trabecular meshwork