The Endocrine System Flashcards
endocrine signaling involves the secretion of [blank] directly into the bloodstream
hormones
[blank] are composed of amino acids and are derived from larger precursor proteins that are cleaved during postranslational modification
peptide hormones
peptide hormones are [blank] and cannot pass through the plasma membrane hint phisochemical property
polar
peptide hormones bind to [blank] receptors where they trigger the transmission of a [blank]
extracellular// second messanger
each step of the [blank] can induce [blank] of the signal
signaling cascade// amplification
peptide hormones exert effects that usually have [blank] onset but are [blank] lived
rapid// short
peptide hormones are [blank] so they travel freely in the blood stream and do not require a special carrier
water-soluble
[blank] are derived from cholesterol
steroid hormones
steroid hormones are [blank] and can pass through the plasma membrane
minimally polar
steroid hormones bind to and promote a conformational change in [blank] or [blank] receptors
cytosolic or intranuclear receptors
the hormone-receptor complex binds to [blank] altering the transcription of a particular gene
DNA
steroid hormones exert effects that usually have [blank] onset but are [blank] lived
slow// long
steroid hormones are [blank] and they cannot dissolve into the bloodstream and must be carried by specific proteins
lipid-soluble
[blank] are modified amino acids
amino acid-derivative hormones
common examples of amino acid-derivatives are…
epinephrine, norepinephrine, triiodothyronine, and thyroxine
hormones can be classified by their [blank]
target tissues
[blank] have major effects on non-endocrine tissues
direct hormones
[blank] have major effects on the endocrine tissues
tropic hormones
the [blank] is the bridge between the nervous system and endocrine systems
hypothalamus
in [blank] the final hormones of a pathway inhibits hormones earlier in the pathway which maintains homeostasis
negative feedback
the hypothalamus stimulates the [blank] gland through paracrine release of hormones into the hypophyseal portal system which directly connects the 2 organs
anterior pituitary
[blank] promotes the release of follicle stimulating hormone (FSH) and luteinizing hormone (LH)
gonadotropin-releasing hormone (GnRH)
[blank] promotes the release of growth hormones
growth hormone-releasing hormone (GHRH)
[blank] promotes the release of thyroid stimulating hormone
thyroid-releasing hormone (TRH)
[blank] promotes the release of adrenocorticotropic hormone (ACTH)
corticotropin-releasing factor (CRF)
[blank] inhibits the release of prolactin
prolactin-inhibiting factor (PIH or dopamine)
the [blank] releases hormones in response to stimulation from the hypothalamus
anterior pituitary
tropic hormones include…
FSH, LH, ACTH, TSH
direct hormones include…
prolactin, endorphins, and growth hormone
[blank] promotes the development of ovarian follicles in females and spermatogenesis in males
follicle-stimulating hormone (FSH)
[blank] promotes ovulation in females and testosterone production in males
lutenizing hormone (LH)
[blank] promotes the synthesis and release of glucocorticoids from the adrenal cortex
adrenocorticotropic hormone (ACTH)
[blank] promotes the synthesis and release of triiodothyronine and thyroxine from the thyroid
thyroid-stimulating hormone (TSH)
[blank] promotes milk production
prolactin
[blank] decrease preception of pain and can produce euphoria
endorphins
[blank] promotes growth of bone and muscle and shunts glucose to these tissues
growth hormone (GH)
the [blank] releases two hormones produced in the hypothalamus
posterior pituitary
[blank] is secreted in response to low blood volume or increased blood osmolarity and increased reabsorption of water in the collecting duct of the nephron , increasing blood volume and decreasing blood osmolarity
antidiuretic hormone (ADH or vasopressin)