The Endocrine System Flashcards
exocrine vs. endocrine glands
exocrine: release enzymes to external environment through ducts
endocrine: release hormones directly into body fluids
3 basic chemistry types of hormones
peptide hormones, steroid hormones, tyrosine derivatives
all peptide hormones manufactured in the …
rough ER –> golgi –> secretory vesicles
intracellular second messenger
activates or deactivates enzyme and/or ion channels, hormone is first messenger
peptide hormones to know
anterior pituitary: FSH, LH, ACTH, hGH, TSH, Prolactin
posterior pituitary: ADH, oxytocin
PTH
pancreatic: glucagon, insulin
steroid hormones derived from…
cholesterol
steroid hormones act at ____ level
transcription, can diffuse through cell membrane, combine with receptor in cytosol, into nucleus
steroid hormones to know
glucocorticoids and mineral corticoids of adrenal cortex: cortisol, aldosterone
gonadal hormones: estrogen, progesterone, testosterone
tyrosine derivatives to know
thyroid hormones: T3 and T4
catecholamines formed in adrenal medulla: epinephrine, norepinephrine
thyroid hormones diffuse into the ___
nucleus, increase transcription
catecholamines act on…
act on receptors at the membrane
anterior pituitary located ….
in the brain beneth the hypothalamus
hGH
human growth hormone
peptide hormone
stimulates growth in almost all cells
ACTH
adrenocorticotropic hormone
peptide hormone
stimulates adrenal cortex to release glucocoricoids (stress hormones) via 2nd messenger system
release of ACTH stimulated by stress
TSH
thyroid stimulating hormone
peptide hormone
stimulates release of T3 and T4, increases thyroid size
prolactin
peptide hormone,
promotes lactation
oxytocin
peptide hormone, from posterior pituitary
uterine contractions, milk ejected from breasts
ADH
antidiuretic hormone
peptide hormone
causes collecting ducts of kidneys to be permeable to water, reducing amount of urine, concentrating urine
increases blood pressure (fluid is absorbed)
adrenal glands
on top of kidneys
cortex:outside portion, only steroid hormones
2 types of steroid hormones secreted from adrenal cortex
mineral corticoids - affect electrolyte balance in blood
glucocorticoids - increase blood glucose concentration, fat and protein metabolism
aldosterone
major mineral corticoid from adrenal cortex, steroid hormone
acts in distal convoluted tubule and collecting ducts
increase in blood pressure from net gain in particles
*Na+ reabsorption and K+ secretion in collecting tubule of kidney
cortisol
steroid hormone, major glucocorticoid
increase blood glucose levels by simulating gluconeogenesis in liver
degrades adipose tissue to fatty acids for energy
stress hormone
catecholamines
tyrosine derivatives, in adrenal medulla
epinephrine and norepinephrine (adrenaline and noradrenaline)
vasoconstrictors of most internal organs and skin, vasodilators of skeletal muscle
fight or flights; stress hormones