The Cytoskeleton Flashcards

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1
Q

what is defined as the cellular scaffolding or skeleton contained with the cytoplasm in all cells?

A

the cytoskeleton

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2
Q

What are the 5 functions of the cytoskeleton

A
  1. it maintains cell shape
  2. protects the cell
  3. enables cellular motion (using structures such as flagella and cilia)
  4. intracellular transport (ie movement of vesicles and organelles)
  5. cell division
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3
Q

name the three different types of cytoskeleton filaments

A
  1. microfilaments (actin)
  2. intermediate filaments
  3. microtubules
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4
Q

Where are microfilaments most concentrated in the cell?

A

just beneath the cell membrane

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5
Q

what are microfilaments comprised of?

A

two intertwined filamentous actin ( F-Actin) chains

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6
Q

which parts of the cytoskeleton are responsible for resisting tension?

A

microfilaments

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7
Q

Which aspect of the cytoskeleton is important for cytokinesis

A

microfilaments

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8
Q

which parts of the cytoskeleton are responsible for maintaining cellular shape

A

microfilaments

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9
Q

which parts of the cytoskeleton are responsible for participating in some cell to cell or cell to matrix junctions?

A

microfilaments (F-actin)

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10
Q

Which aspect of the cytoskeleton is important for muscular contraction (with myosin)?

A

microfilaments

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11
Q

Which aspect of the cytoskeleton is important for cytoplasmic streaming (with myosin)

A

microfilaments

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12
Q

what diameter are intermediate filaments

A

8-10 nanometers

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13
Q

Where are intermediate filaments found in the cell?

A

throughout the cell

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14
Q

Why are intermediate filaments more stable than microfilaments?

A

they are more strongly bound than actin filaments

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15
Q

what is vimetin

A

Vimentin is a structural protein that in humans is encoded by the VIM gene. Its name comes from the Latin vimentum which refers to an array of flexible rods.

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16
Q

what is keratin

A

one of a family of fibrous structural proteins known as scleroproteins. α-Keratin is a type of keratin found in vertebrates. It is the key structural material making up hair, nails, feathers, horns, claws, hooves, calluses, and the outer layer of skin among vertebrates.

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17
Q

which aspect of the cytoskeleton can be composed of vimetins

A

intermediate filaments

18
Q

which aspect of the cytoskeleton can be made of keratin

A

intermediate filaments

19
Q

which aspect of the cytoskeleton is found in neural cells

A

neurofilaments

20
Q

which aspect of the cytoskeleton is very dynamic in behaviour (constantly elongates and shortens)

A

microtubules

21
Q

which aspect of the cytoskeleton is made of alpha and beta tubulin

A

microtubules

22
Q

which aspect of the cytoskeleton is able to resist compression compared with other cytoskeletal filaments

A

microtubules

23
Q

how wide is the lumen of a mictotubule

A

15 nanometers

24
Q

which cytoskeletal filament is arranged in an imperfect helix

A

microtubule

25
Q

which cytoskeletal filament is composed of two heterodimers ( a and b tubulin)?

A

microtubule

26
Q

which cytoskeletal filament has polarity

A

microtubule (due to alpha-tubulin at one end and beta-tubulin at the other)

27
Q

how many tubulin dimers does each turn of the microtubules helix have?

A

13 tubulin dimers each from a different protofilament

28
Q

what is a protofilament

A

A protofilament is a linear row of tubulin dimers

29
Q

which cytoskeletal filament plays a key role in Intracellular transport (they transport organelles like mitochondria or vesicles)

A

microtubules

30
Q

which cytoskeletal filament plays a key role in the cytoskeleton (axoneme) of cilia and flagella

A

microtubules

31
Q

which cytoskeletal filament plays a key role in synthesis of the cell wall in plants?

A

microtubules

32
Q

which cytoskeletal filament plays a key role in The mitotic spindle?

A

microtubules

33
Q

what organelle can microtubules form?

A

centrioles

34
Q

how are the microtubules in centrioles arranged?

A

9 triplet sets

35
Q

what organelle is involved in the organisation of the mitotic spindle and in the completion of cytokinesis

A

centrioles

36
Q

what form cilia and flagella

A

microtubules

37
Q

how are the microtubules oriented in cilia or flagella?

A

9+2 arrangement; Microtubules are in nine doublets oriented about two additional microtubules (wheel-shaped)

38
Q

Which part of the cytoskeleton thickens the cortex around the inner edge of a cell and resist tension like rubber bands?

A

microfilaments

39
Q

Which part of the cytoskeleton are found in the interior of the cell where they maintain cell shape by resisting compressive forces?

A

microtubules

40
Q

Which part of the cytoskeleton is found throughout the cell and hold organelles in place.

A

intermediate filaments