Cells and Tissues of the Immune System

Question 1

What is haematopoiesis

Answer 1

the formation of blood cellular components. (All cellular blood components are derived from haematopoietic stem cells)

Question 2

in what tissue are pluripotent hematopoietic stem cells found

Answer 2

bone marrow

Question 3

common lymphoid progenator cells specialise into which 3 immune cell types

Answer 3

B cells
T cells
NK cells

Question 4

erythroblasts are precursor cells to which cell

Answer 4

erythrocytes (RBCs)

Question 5

What are the 3 effector cells?

Answer 5

plasma cell
activated T cell
activated NK cell

Question 6

megakaryocytes are precursors to which component of blood

Answer 6

platelets

Question 7

where are the granulocytes found?

Answer 7

the blood

Question 8

a neutrophil is part of which hematopoietic lineage?

Answer 8

granulocyte

Question 9

an eosinophil is part of which hematopoietic lineage?

Answer 9

granulocyte

Question 10

a basophil is part of which hematopoietic lineage?

Answer 10

granulocyte

Question 11

a monocyte is part of which hematopoietic lineage?

Answer 11

granulocyte

Question 12

common myeloid progenitor cells produce which 2 types of progenitor cell

Answer 12

granulocyte/macrophage progenitor

megakaryocyte/erythrocyte progenitor

Question 13

unknown precursor of mast cells are part of which hematopoietic lineage?

Answer 13

granulocytes

Question 14

which immune cells are found in the lymph nodes

Answer 14

B cell
T cell
NK cell

Question 15

immature dendritic cells found in the blood end up as what and where are they found?

Answer 15

mature dendritic cells in tissues and lymph nodes

Question 16

where are mast cells found

Answer 16

in tissues

Question 17

where are macrophages found

Answer 17

in tissues

Question 18

what is the normal cell % for basophils

Answer 18

<1%

Question 19

what is the normal cell % for eosinophils?

Answer 19

1-3%

Question 20

what is the normal cell % for monocytes?

Answer 20

1-6%

Question 21

what is the normal cell % for lymphocytes

Answer 21

20-40%

Question 22

what is the normal cell % for neutrophils

Answer 22

50-70%

Question 23

what is the normal cell count for RBCs

Answer 23

5.0 x 10~6 cells/mm3

Question 24

what is the normal cell count for platelets

Answer 24

2.5 x 10~5 cells/mm3

Question 25

what is the normal cell count for leukocytes

Answer 25

7.3 x 10~3 cells/mm3

Question 26

which progenitor cells produces macrophages

Answer 26

monocytes

Question 27

where is the alveolar macrophage found?

Answer 27

lung tissue

Question 28

where are histiocytes found

Answer 28

connective tissue

Question 29

where are mesangial cells found

Answer 29

kidney

Question 30

where are microglial cells found

Answer 30

brain

Question 31

where are kupffer cells found

Answer 31

liver

Question 32

where are osteoclasts found

Answer 32

bone

Question 33

Stem cell --> ? --> ? ---> macrophage

Answer 33

monoblast | monocyte

Question 34

what do macrophages differentiate into?

Answer 34

microglia kupffer cells alveolar macrophages osteoclasts etc

Question 35

what do macrophages turn into upon immune activation?

Answer 35

activated macrophages