the component of the immune system Flashcards

1
Q

what does immunity mean

A

Immunity is body’s ability to resist or eliminate potentially harmful foreign materials or abnormal cells

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2
Q

what is innate immunity?

A

The first line of defense always ready to prevent and eradicate infections

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3
Q

what is adapative immunity?

A

Develops later, after exposure to microbes, and is even more powerful than innate immunity in combating infections

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4
Q

what are the components of innate immunity?

A

-natural barriers
-phagocytes
-soluable meditors e.g comlement

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5
Q

what are the adpative components of immunity?

A

lymphocytes
-antigen pressig cells
anitgen recongistion molecules

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6
Q

describe innate immunity?

A

Provides immediate protection from infection
Is broadly specific to microbes and tissue damage products
Initiates processes that lead to activation of adaptive immune responses.
Does not change in response to reinfection (non- adaptive)

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7
Q

describe adaptive immunity?

A

Is highly specific to a particular molecule “antigen
Generates proteins and cells that enhance innate immune function.
Responses upon reinfection are faster, better and stronger (memory)

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8
Q

what are some external defenses

A

skin
mucous membranes
ssecretions

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9
Q

what are some internal defenses

A

phagocytic cells
antimicrobial proteins
inflammatory response

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10
Q

what are some acquired immunity responses

A

humoral response
cell mediated response

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11
Q

what are phaycytes?

A

a cell such a WBC that engulfs and absorbs waste material and other harmful microorganisms or any other foreign bodies in the blood stream

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12
Q

what is the lifespan of moncytes

A

days

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13
Q

what is the lifespan of macrophages

A

several months or even years

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14
Q

describe monocytes and macrophages

A

Spend only a short time in the marrow, and after circulating for 20-40hrs, leave the blood to enter the tissues

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15
Q

what is the function of monocytes and macrophages

A

Assume specific functions in different tissues: brain/microglia; lung/alveolar

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16
Q

what are the 3 functions of monocytes and macrophage

A

1) destroy bactiera by phagocytosis
2) activate other immune functions
3) phagocytose apoptotic cells

17
Q

describe neutrohils?

A

Neutrophils are a type of granulocytic white blood cell.

Form an essential part of the innate immune system, in response to bacterial infections

Dense nucleus, consisting of 2-5 lobes, irregular outline

18
Q

why are neutrophills important?

A

Neutrophils are one of the first-responders of inflammatory cells to migrate towards the site of inflammation

19
Q

describe the cytoplasm in neutrophills?

A

Pale cytoplasm, containing fine pink-blue or grey-blue granules

20
Q

what % does esoniphill make up of the wbc

A

1.5%

21
Q

what does eosinophil also possess?

A

anti histamine properties

22
Q

what does esoniphill cells do>

A

cells migrate to the area of the bodt were they are exposed to the external envrionment usually under the skin.

23
Q

describe basophill?

A

Basophils are the smallest circulating granulocytes and they contain heparin and histamine

The number of basophils increases during infection.

24
Q

what does basophill secrete?

A

They accumulate at the site of infection or other inflammation, were they secrete histamine, which increase the blood flow to the infected area.

25
Q

what % of basophills show up as WBC

A

0.5%

26
Q

what do basophills assist with?

A

they assist the movement of phagocytes and protective substances such as antibodies, into the tissue spacing, were they accumulate in areas of local inflammation at the healing stage

27
Q

what are mast cells?

A

Mast cells play a central role during allergic reactions

28
Q

where do mast cells live?

A

directly under the skin and mucosae, and react immediately when an allergenic substance enters the body

29
Q

quick summary of neutophill

A

diameter 10-12

target: bacteria and fungi

LS: 6 hours to a few days

30
Q

quick summary of eosinophil?

A

diamter 10-12

targets: parasite in allergic reactions

LS: 8-12 DAYS

31
Q

quick summary of basophill?

A

diamter: 12-15 nanometers

targets: allergic reactions

32
Q

quixk summary of lymphcytes?

A

daimter 7-8 nanonmeters

targets: B cells” various pathogens
t cells: inflam t cell, helper t cell

natural killer cells

LS: weeks to years

33
Q

what are the diff types of WBC

A

neutrophil
esopinhill
basophill
lymphocyte
monocyte
macrphage
dendric cells

34
Q

which are the phayocytic cells

A

Neutrophils
Macrophages
Monocytes
Dendritic cells

35
Q
A