organs of the immune system Flashcards

1
Q

what are lymphoid organs?

A

parts of the immune system that play a crucial role in the body’s defense against infections and diseases.

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2
Q

what are the lymphoid organs responsible for?

A

production and maturation of lymphocytes,

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3
Q

what are the key lymphoid organs?

A

bone marrow
thymus
spleen
lymph nodes
Tonsils and Adenoids
Peyer’s Patches

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4
Q

summarise the primary lymphoid organs- bone marrow

A

bone marrow site of generation of all circulating blood cells in an adult including immature lymphocytes and is site of b cell maturation

site of differentiation and maturation of WBC

site of immune response of b cells specifically in secondary immune response

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5
Q

summarise lymphoid organs - thymus

A

both t cells and b cells are ‘born’ in the bone marrow

  • b cells can mature in the bone marrow whereas t cells have to mature in the thymus (where they move to)
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6
Q

what happens to immature lymphocytes?

A

become committed within the primary lymphoid organs

Only after maturation has occurred that cell is IMMUNOCOMPETENT

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7
Q

what are the secondary lymphoid organs?

A

adenoids
peyers patches
appendix

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8
Q

what is the function of the lymph nodes?

A

contain high concentrations of leukocytes that filter out microbes and toxins

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9
Q

what is the function of spleen>

A

of the blood circulatory system has the same function as the lymph nodes

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10
Q

how can the lymph nodes and the spleen may be affected?

A

infected by the organisms that have collected
during filtration

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11
Q

summarise the lymphatic system? 1/3

A

As blood circulates under pressure, plasma seeps through thin walls of capillaries.

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12
Q

summarise the lymphatic system? 2/3

A

Much of this fluid returned to blood but some enters lymphatic system, which is referred to as “lymph”.

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13
Q

what is the structure of a lymph node?

A

outer cortex- filled with lymph follicles

outer edge of follicle contains more t cells

inner germinal center is the site of b cells prolifeeration

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14
Q

summarise the lymphatic system? 3/3

A

When a foreign antigen gains entry to the tissues, it is picked up by lymphatic system and taken to lymph nodes that trap the antigen

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15
Q

what is the inner medulla of the lymph node responsible for?

A

medullary cords of the lymphcytes, macrophages, plasma cells (activated b cells)

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16
Q

what can the fibres of the lymph node act as?

A

net to catch any debris or cells that are present in the lymph

17
Q

reticular fibres?

A

Macrophages and lymphocytes attack and kill any microbes caught in the reticular fibers.

18
Q

what is extravasation?

A

immune cells travel back and forth from the blood and lymph CS and interact with extra vascular tissues in the process

19
Q

what is extravasation? simple

A

escape of fluid, cells, or other substances from blood vessels into surrounding tissues

20
Q

what can cause extravasation?

A

including inflammation, injury, or certain medical procedures

21
Q

what is lymph?

A

a fluid containing
-water
-sugars
-wbc
-protein

22
Q

what are lymph vessels

A

carry lymph within the lymphatic system

lymph capillaries are the smallest of the lymph vessels

23
Q

how do leukocytes travel from one system to another

A

Lymph carrying antibodies
and immune cells collect in
thoracic duct where the
lymph empties back into the
blood circulatory system

24
Q

what happens when the lymphatic system goes wrong?

A

lymphatic filariasis- symptoms` include swelling and enlargement of the arms and legs

25
Q

People with elephantiasis have what?

A

impaired immune function due to damage to the lymph system

26
Q

summarise the spleen?

A

largest lymphoid tissue

27
Q

what are the functions of the spleen

A

Filters out older RBCs
Responds to Antigens in circulatory system
Produces activated B cells
Stores platelets
In fetus: site of haematopoiesis

28
Q

what happens when the spleen gets damaged?

A

; splenectomy increases risk of bacterial infection

29
Q

describe the tonsils?

A

masses of lymph tissue designed to filter tissue fluid, not lymph

30
Q

what is tissue fluid?

A

Tissue fluid, also known as interstitial fluid or extracellular fluid, is a clear, colorless fluid that surrounds the cells within tissues.

31
Q
A