the central nervous system 1 Flashcards
cephalization
evolutionary development of the rostral (anterior) portion CNS - results in an increased number of neurons
4 regions of the adult brain
- cerebrum (2 hemispheres)
- diencephalon
- brain stem (midbrain, pons, medulla oblongata)
- berebellum
gray matter
short, non mylinated neurons + cell bodies
white matter
mostly myelinated axons, some nonmyelinated axons, primarily organized in fiber tracts
basic pattern of the CNS
central cavity surrounded by gray matter with white matter external to the gray matter - this pattern is seen in the spinal cord
- the brain stem has additional gray matter nuclei scattered within the white matter
- the cerebral hemispheres and cerebellum contain an outer layer of gray matter (the cortex)
ventricles
fluid filled chambers
- filled with cerebrospinal fluid (CSF) and lined with ependymal cells
- the ventricles are continuous with one another and with the central canal of the spinal cord
lateral ventricles
large, paired, c-shaped chambers, deep within each hemisphere
- each lateral ventricle is connected to the narrow 3rd ventricle via interventricular foramen
- the 3rd ventricle connects to the 4th ventricle cerebral aqueduct - the 4th ventricle is continuous with the central canal of the spinal cord
3 openings that connect the 4th ventricle to the subarachnoid space
- paired lateral apertures
- 1 median aperture
septum pellucidum
thin membrane that separates the lateral ventricles
cerebral hemispheres surface markings
- gyri: ridges
- sulci: shallow grooves
- fissures: deep grooves
longitudinal fissure
separates the 2 hemispheres
transverse cerebral fissure
separates cerebrum and cerebellum
5 cerebral hemispheres
- frontal
- parietal
- temporal
- occipital
- insula
3 major sulci
- central sulcus: separates the precentral gyrus of the frontal lobe and the postcentral gyrus of the parietal lobe
- parieto-occipital sulcus: separates the occipital and parietal lobes
- lateral sulcus: outlines the temporal lobes
3 basic regions of each cerebral hemisphere
- cerebral cortex: superficial gray matter
- internal white matter
- basal nuclei: islands of gray matter deep within white matter
cerebral cortex
- The “executive suite” of the brain
- Thin (2-4mm), superficial layer of gray matter
- Site of the conscious mind: awareness, sensory perception, initiation of voluntary motor tasks, communication, memory storage, understanding
- Composed of neuron cell bodies, dendrites, glial cells, and blood vessels – no axons!
- Contains billions of neurons; accounts for 40% of the mass of the brain
functional imaging
pet scans and/or functional MRI can show where specific motor and sensory functions
- show metabolic activity
- functional mris show blood flow
domain
the place a particular motor or sensory function is localized
- the higher functions (memory, language, etc) are spread over multiple areas and in overlapping domains
4 general considerations of the cerebral cortex
1.The cortex contains 3 types of functional areas:
- Motor Areas: control voluntary movement
- Sensory Areas: conscious awareness of sensation
- Association Areas: integrate diverse information
2. Each hemisphere is chiefly concerned with the sensory and motor functions of the contralateral (opposite) side of the body
3. Although largely symmetrical in structure, the two hemispheres are not identical in function
- Lateralization: specialization of cortical function in only one hemisphere
4. Conscious behaviors involve the entire cortex
cerebral cortex: motor areas
The motor areas are located in the posterior part of the frontal lobe. They control most voluntary movement.
- Primary Motor Cortex: located in the precentral gyrus
- Premotor Cortex: anterior to the precentral gyrus
- Broca’s Area: anterior and inferior to the premotor cortex
- Frontal Eye Field: within and anterior to the premotor cortex; superior to Broca’s area
cerebral cortex: the primary motor cortex
The primary motor cortex is in the precentral gyrus of the frontal lobe
- Pyramidal Cells: large neurons that allow conscious control of precise, skilled skeletal muscle movements
- Pyramidal (Corticospinal) Tracts: formed from the long axons of the pyramidal cells that project down to the spinal cord
- Somatotopy: all specific areas of the body can be mapped to specific areas on the primary motor cortex
- Motor Homunculi: upside-down, caricature-like representation of the motor innervation of the contralateral body regions
Cerebral Cortex: Other Motor Areas
Premotor Cortex
- Helps to plan movements – a “staging area”
- Selects + sequences basic motor movements into more complex tasks
- Uses highly processed sensory information to control voluntary actions
- Sends activating impulses to the primary motor cortex
Broca’s Area
- Present in only 1 hemisphere – usually the left
- Motor speech area – directs the muscles of speech production
- Active in planning speech and other voluntary motor activities
Frontal Eye Field
- Located partially in and anterior to the premotor cortex
- Controls voluntary eye movements
damage to the primary motor cortex
– as seen in strokes – paralyzes the muscles controlled by those areas
- Paralysis will occur on the opposite side of the body from the cortical damage
- Only voluntary control is lost – the muscles can still contract reflexively
Damage to the premotor cortex
results in loss of the motor skills programmed by that region, but it does not impair muscle strength or the ability to perform discrete, individual movements
- Other premotor neurons can be reprogrammed to take over the skill of the damaged neurons, but this requires significant patience and practice