The Cell Study Guide Flashcards

1
Q

What are the 3 tenets of cell theory?

A
  1. the cell is the basic unit of life
  2. all cells come from preexisting cells
  3. all organisms are made of cells
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2
Q

Do all your human cells look the same? Function the same? Contain the same genetic material?

A

No (over 250 diff types of human cells)

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3
Q

List 5 different types of cells in the human body. Think of an example where 1 of those cell types might have more of a particular type of organelle than the others because of it’s function.

A
  • nerve cells
  • sperm cells
  • fat cells
  • epithelial cells
  • cardiac (muscle) cells (more mitochondria because it requires more energy production)
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4
Q

Be able to list the 3 types of extracellular material – and the 3 types of extracellular fluid!

A

Extracellular material:
- Extracellular fluid
- cellular secretions
- extracellular matrix

Extracellular fluid:
- interstitial fluid
- blood plasma
- cerebrospinal fluid

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5
Q

What is glycocalyx? What is its function?

A
  • sugars (carbohydrates) sticking out of cell surface, sometimes attached to lipids or proteins
  • functions as cell-to-cell recognition and allows immune system to tell if that cell is a friend or foe
  • mutated cells evade immune system by changing their glycocalyx often
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6
Q

What type of lipid is most common in a plasma membrane?

A

phospholipids

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7
Q

Compare/contrast integral vs peripheral proteins.

A

Integral proteins:
- transport proteins (channels and carriers), enzymes, or receptors

Peripheral proteins
- loosely attached to integral proteins
- function as enzymes, motor proteins for shape change during motor contraction or cell division, cell-to-cell connections

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8
Q

What are the 3 types of cell junctions? What is the structure + function of each type? Give an example of where you might find each different type.

A
  1. tight junctions
    - integral proteins on adjacent cells that do not allow fluids and most molecules to move in between cells
    - found in lining of digestive tract
  2. desmosomes
    - anchoring junction that acts like velcro
    - some give between cells to reduce possibility of tearing under tension
    - found in heart and skin muscle
  3. gap junctions
    - transmembrane proteins form tunnels that allow small molecules to pass from cell-cell
    - allow electrical signals to pass from one cell to the next
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9
Q

What does it mean to be “selectively permeable”?

A

some molecules pass through easily, some do not

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10
Q

What is the main difference in active vs passive transport?

A

active transport requires energy (ATP) while passive does not

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11
Q

What’s a concentration gradient? How do molecules typically move?

A

the difference in the concentrations
- molecules move down their concentration gradient
(from higher to lower concentration)

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12
Q

Define diffusion. Differentiate simple vs facilitated diffusion.

A

diffusion: movement of molecules through the plasma membrane to lower concentrations from higher ones
simple diffusion: movement of hydrophobic particles from high to low concentration without a protein
facilitated (active) diffusion: carrier or channel mediated

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13
Q

What’s the difference between carrier and channel media facilitated diffusion?

A

carrier mediated: substances bind to specific transmembrane protein carriers (saturation-binding limited by the # of carriers present)
channel-mediated: substances move through water-filled channels

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14
Q

Define osmosis, osmolarity, and equilibrium.

A

osmosis: diffusion of a solvent (often water) across a selectively permeable membrane by channel (aquaporin) or lipid bilayer 9occurs when concentration of water is different on 2 sides of membrane
- osmolarity: total concentration of all solute particles in a solution
Eqilibrium: state of same concentration of solute and water molecules on both sides (volume may or may not be equal)

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15
Q

Be ready to state what will happen to cells placed into hypotonic, hypertonic, and isotonic solutions.

A

Hypertonic: cell will shrivel
Hypotonic: cell will swell and possibly undergo lysis (explode)
Isotonic: cell will remain at normal size

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16
Q

Define and compare/contrast primary active, secondary active, and vesicular transport.

A

primary active: energy required comes directly from the hydrolysis of ATP by transport proteins called pumps (sodium-potassium pump)
secondary active: driven by energy stored in the concentration gradients of ions created by primary active transport
Vesicular transport: transport of large particles, macromolecules, and fluids across a membrane in sacs called vesicles

17
Q

Define antiporters and symporters.

A

antiporters: transport 1 substance into the cell and 1 different substance out of a cell
symporters: transport 2 different substances in the same direction

18
Q

Be very familiar with the workings of a sodium-potassium pump! What do functioning sodium-potassium pumps help to maintain?

A
  • maintains negative polarity of the cell
  • pumps 2 potassium in and 3 sodium out against their gradients
19
Q

Define endocytosis, exocytosis, transcytosis, and vesicular trafficking. What happens in phagocytosis and pinocytosis?

A

endocytosis: transport into cell
- phagocytosis: eating action
- pinocytosis: drinking action
exocytosis: transport out of the cell
transcytosis: into, across, and out of a cell
vesicular trafficking: transport form 1 are/organelle within a cell to another area

19
Q

Know the difference between cytoplasm and cytosol.

A

cytoplasm: cellular material between the plasma membrane and nucleus made up of cytosol, inclusions, and organelles
- cytosol: gel like solution with proteins, salts, and sugars inside it
*cytoplasm contains organelles and cytosol does not

20
Q
A
21
Q

What cell organelles are part of the endomembrane system? What does the endomembrane system do?

A

endomembrane organelles
- ER, Golgi apparatus, secretory vesicles, lysosomes, nuclear and plasma membranes
endomembrane function: produce, degrade, store, and export biological moleculee. degrade potentially harmful substances

21
Q

Know the main function(s) of the mitochondria, ribosomes, golgi apparatus, peroxisomes, and lysosomes.

A
  • mitochondria: produces ATP
  • ribosomes: site of protein synthesis
  • golgi apparatus: modified and packages proteins/lipids
  • peroxisomes: detoxify substances in the cell
  • lysosomes: cleaning crew (like lysol), digests ingested bacteria, viruses, toxins, degrades nonfunctional organelles
21
Q

Know the equation for cellular respiration.

A

c6h12o6+6o2 –> 6co2+6h2o+atp

21
Q

What is the cytoskeleton? What 3 types of rods does it contain?

A

Cytoskeleton: network of rods that run through cytosol and act as the cell’s bones, ligaments, and muscle. like the train tracks for cargo
Three types:
- microfilaments
- intermediate filaments
- microtubules

21
Q

What’s the difference in function between cilia, flagella, and microvilli?

A

cilia: short multitude of projections that aid in movement of substances surrounding the cell surface
flagella: long tail like projection that aids in movment
- micrvoilli: assist in absorption

21
Q

What’s the difference between chromatin and chromosomes?

A

chromatin condenses into chromosomes

21
Q

What is contained within the cell’s nucleus? What’s the nuclear lamina?

A
  • contains blueprints for synthesizing nearly all cellular proteins
  • contains nuclear envelope, nucleolus, chromatin
  • nuclear lamina = network of proteins that maintain the nuclear shape and acts as scaffolding for DNA (ring around inside of nucleus)
21
Q

Smooth ER

A
  • lipid metabolism, synthesis of cholesterol and steroid-based hormones, synthesis of lipids for lipoproteins
  • absorption, synthesis, and transport of fats
  • detoxification of chemicals (drugs, pesiticides)
  • converting glycogen to free glucose
  • storage and release of calcium
22
Q

Rough ER

A
  • synthesizes proteins that will be secreted from the cell
  • synthesizes plasma membrane proteins and phospholipids
  • proteins enter the cisterns and get modified as they wind through fluid-filled tubes
  • final protein produces are enclosed in a vesicle and go to the golgi apparatus for processing