The Cell - Anatomy and Physiology Laboratory Flashcards
fundamental unit of life
cell
Cells of the human body are classified as
eukaryotic
is a thin phospholipid bilayer in which
various proteins are embedded or attached
plasma membrane
hydrophilic
water-loving
hydrophobic
water-fearing
The phospholipids are composed of
hydrophilic (“water-loving”) phosphate heads and hydrophobic (“water-fearing”) lipid tails.
Two types of proteins are associated with the phospholipid bilayer:
Integral proteins and peripheral proteins
are embedded at least partially within
the cell membrane
integral proteins
are located on the interior or exterior surface of the cell membrane.
peripheral proteins
Some integral proteins, called _________________________, span the entire width of the phospholipid bilayer.
transmembrane proteins
A plasma membrane is
selectively permeable
allows the passage of some substances but not others
selectively permeable
Nonpolar molecules such as_____________________________________ pass freely through the membrane
oxygen, carbon dioxide, and steroid hormones
water-soluble substances, such as _____________________________________________ are unable to pass freely through the membrane.
amino acids, sugars, proteins, nucleic acids, and many ions
can serve as transport channels through which substances move from one side of the membrane to the other.
Integral proteins
Cells depend on the ____________________ to import substances such as nutrients, oxygen, and hormones, and to export substances such as carbon dioxide and other waste products.
selectively permeable plasma membrane
Both integral and peripheral proteins can serve as _______________________ and they also play major roles in cell-to-cell recognition and intercellular joining.
receptors and enzymes
A cell’s membrane transport mechanisms are of two types:
passive and active
in which substances cross the membrane without the cell expending any energy,
passive
requires the cell to expend energy in the form of the high-energy molecule ATP.
active
Among passive transport mechanisms the most common
are
diffusion and osmosis
Passive transport mechanisms can be either
unassisted or assisted
The unassisted net movement of molecules from an area of higher concentration to an area of lower concentration is called
simple diffusion
requires the assistance of either a channel protein (channel- mediated facilitated diffusion) or a carrier protein (carrier-mediated facilitated diffusion)
facilitated diffusion
assistance of a channel protein
channel- mediated facilitated diffusion
assistance of a carrier protein
carrier-mediated facilitated diffusion
is a special type of diffusion involving the passive movement of a solvent (usually water) from an area of higher water concentration (and thus lower solute concentration) to an area of lower water concentration (and thus higher solute concentration) across a selectively permeable membrane, either through the phospholipid bilayer or through a specific channel protein called an aquaporin
Osmosis
substances are driven through a selectively permeable membrane by hydrostatic pressure.
filtration
Two common energy-requiring transport mechanisms are termed
active transport and vesicular transport
is the movement of molecules from an area of lower concentration to an area of higher concentration and is accomplished with the expenditure of energy.
Active transport
is a classic example of an active transport mechanism
sodium-potassium pump
of a cell consists of a variety of specialized structures called organelles suspended in a fluid portion called the cytosol, which is largely water containing a variety of solutes such as sugars, proteins, and ions. Organelles perform specific functions to maintain homeostasis within the cell.
cytoplasm
is largely water containing a variety of solutes such as sugars, proteins, and ions.
cytosol
perform specific functions to maintain homeostasis within the cell.
organelles
Note that the cytosol of some cells also contains _____________
inclusions
are stored cellular products
inclusions
Note that the cytosol of some cells also contains inclusions, which are stored cellular products such as
glycogen granules (in muscle fibers and liver cells), lipid droplets (in adipocytes), and pigment granules (in certain skin cells).
in muscle fibers and liver cells
glycogen granules
in adipocytes
lipid droplets
in certain skin cells
pigment granules
is the control center of the cell
nucleus
single nucleus
uninucleate
lacks a nucleus
anucleate
example of multinucleate cells are
skeletal muscle fibers and liver cells
examples of cells that lacks a nucleus
mature red blood cell
The nucleus is surrounded by a double-layered
nuclear envelope
that regulate the movement of substances into and out
of the nucleus
nuclear pore
are round, dark-staining structures that function in ribosome synthesis
nucleoli
which is composed of tightly coiled DNA (the genetic material), proteins, and RNA.
chromatin
Synthesizes proteins.
Ribosome
Synthesizes and transports proteins.
Rough endoplasmic reticulum (RER)
Synthesizes lipids and steroids (cholesterol); detoxifies drugs.
Smooth endoplasmic reticulum (SER)
Packages and modifies proteins.
Golgi apparatus
Synthesizes ATP; is the “powerhouse” of the cell.
Mitochondrion
Contains enzymes that digest worn-out organelles and substances that have entered the cell.
Lysosome
Detoxifies toxic substances.
Peroxisome
Organizes the mitotic spindle during cell division.
Centrosome with centrioles
Support the cell and give it shape; are components of centrioles, cilia, and flagella; form spindle apparatus during mitosis; transport organelles and structures within the cell.
Microtubules
Strengthen the cell and help maintain its shape; stabilize the position of organelles.
Intermediate filaments
Anchor the cytoskeleton to integral proteins of the plasma membrane; enable cellular movements.
Microfilaments
consists of the series of events that occur in the life of a cell
cell cycle
The cell cycle is divided into two major parts
interphase and mitotic phase
during which the cell grows and is metabolically active
interphase
during which the cell divides
mitotic phase
Interphase is further subdivided into three
subphases:
G1, S, and G2.
the cell grows, produces additional organelles, and is metabolically active.
G1 phase
the cell begins to replicate its centrioles in preparation for cell division.
Toward the end of G1
replication (DNA synthesis) occurs
S phase
the cell makes an identical copy of its genetic material so that each daughter cell produced during the mitotic phase will have one complete set of chromosomes and will be genetically identical to the parent cell.
replication
the cell continues to grow, synthesizes the proteins necessary for cell division, and completes the production of new centrioles.
G2 phase
Note that some mature, highly specialized cells (such as _____________________) instead enter an indefinite G0 phase and never enter the mitotic phase.
skeletal muscle fibers and neurons
Note that some mature, highly specialized cells (such as skeletal muscle fibers and neurons) instead enter an indefinite ___________ and never enter the mitotic phase.
G0 phase
The mitotic phase of the cell cycle consists of two specific
events:
mitosis and cytokinesis
division of the nucleus
mitosis
division of the cytoplasm
cytokinesis
Mitosis is divided into four phases:
prophase, metaphase, anaphase, and telophase.
the chromosomes (each consisting of two sister chromatids
held together by a centromere) coil and become visible, the
nuclear envelope breaks down, the centrioles move to opposite poles of the cell, and the mitotic spindle forms.
prophase
the chromosomes line up along the metaphase plate (equator)
metaphase
the sister chromatids of each chromosome split apart and move to opposite poles of the cell.
anaphase
the sister chromatids reach the opposite poles and uncoil to become chromatin once again as new nuclear envelopes form around each mass of chromatin.
telophase
begins during anaphase and continues through and beyond telophase.
cytokinesis
is completed by the formation of two daughter cells, each of which is genetically identical to the parent cell.
cytokinesis