Integumentary System - AnaPhy Lab Pt. 2 Flashcards
is composed of the skin, or cutaneous membrane, plus its accessory structures: hairs, nails, and glands.
INTEGUMENTARY SYSTEM
the largest and most visible organ of the body
skin
Functions of the Skin
Protection - by forming an impenetrable barrier to infectious agents.
Excretion - Through the excretion of sweat, waste products (including lactic acid and urea) are released onto the skin.
Sensations - Numerous sensory receptors in the skin enable sensations, such as touch, pain, temperature, pressure, and vibration.
Thermoregulation - Blood vessels and sweat glands in the skin enable it to act in thermoregulation by removing excess heat or preventing heat loss.
Synthesis of vitamin D - the skin is the site of the initial steps in the synthesis of vitamin D, which is important for the absorption of calcium from the diet.
The skin is made up of two distinct layers:
- the superficial epidermis
- underlying dermis
A third layer of tissue that lies deep to the dermis
hypodermis
consists of loose connective tissue with many blood vessels and adipose tissue
hypodermis
hypodermis consists of
loose connective tissue with many blood vessels and adipose tissue
is avascular and composed of keratinized, stratified squamous epithelium and contains four distinct cell types
Epidermis
four distinct cell types of the Epidermis
- keratinocytes
- melanocytes
- dendritic (Langerhans) cells
- Merkel (tactile) cells
produce the strong waterproofing protein keratin
keratinocytes
produce the protective pigment melanin
melanocytes
are specialized white blood cells that migrate to the epidermis, where they function as phagocytes
Dendritic (Langerhans) cells
are located at the epidermal–dermal junction and function in light touch reception.
Merkel (tactile) cells
thick skin is located where
only in the palms of the hands and the soles of the feet
thick skin has how many strata/layers?
five
layers of thick skin (from top to bottom)
stratum corneum
stratum lucidum
stratum granulosum
stratum spinosum
stratum basale
thin skin is located where
everywhere else in the body
thin skin contains how many layers?
4
what strata is absent in thin skin?
stratum lucidum
the deepest layer of the epidermis
Stratum Basale
consists of a single layer of cuboidal epithelial cells (keratinocytes) attached to a basement membrane.
Stratum Basale
what cells are present in stratum basale?
keratinocytes and melanocytes
contains 8–10 layers of cells, mostly keratinocytes that have a “spiny” appearance in histological preparations.
Stratum Spinosum
what cells are prominent in stratum spinosum?
keratinocytes, dendritic cells
thin and consists of three to five layers of keratinocytes that undergo a drastic change in appearance as they begin to fill with keratin (a process called keratinization)
Stratum granulosum
the cells flatten and their organelles, including the nucleus, disintegrate; the cells eventually die.
Keratinization
The rods of cells move upward through the skin as new cells form beneath them. As they move up, they’re cut off from their supply of nourishment and start to form a hard protein called keratin
Keratinization
stratum lucidum is found only in the
thick skin of the palms and soles
found only in the thick skin of the palms and soles
stratum lucidum
consists of two to four translucent layers of flat, dead keratinocytes.
stratum lucidum
The most superficial epidermal stratum
Stratum corneum
is the thickest stratum, consisting of 20–30 layers of cells
Stratum corneum
highly vascular
dermis
dermis consists of:
papillary layer and reticular layer
lies immediately deep to the stratum basale and largely consists of loose connective tissue
Papillary Layer
it contains finger-like projections called dermal papillae, many of which contain capillary loops that provide a blood supply to the overlying, avascular epidermis.
Papillary Layer