The Basics of Metabolism

Question 1

intermediates in metabolic paths referred to as:

Answer 1

metabolites

Question 2

what is an amphibolic path?

Answer 2

can function anabolically or catabolically

Question 3

When Keq=1, delta G=__; when Keq=1, delta G=__

Answer 3

0; positive value; negative value

Question 4

to make a metabolic path, these 2 criteria need to be met:

Answer 4

1) individual rxn must be specific

2) path in total needs to be thermodynamically favourable

Question 5

UTP is involved in ___ metabolism; GTP is involved in ___ synthesis; CTP is involved in ___ synthesis

Answer 5

carb; protein; lipid

Question 6

what are the 3 key factors for why ATP has a high P-transfer potential?

Answer 6

charge repulsion, resonance stabilization, stabilization by hydration

Question 7

what are the high energy compounds?

Answer 7

PEP, 1,3-BPG, creatine phosphate (muscle)

Question 8

what are the low energy compounds?

Answer 8

glucose-6-P, glycerol-3-P

Question 9

oxidation is:

Answer 9

loss of electrons, sometimes also protons

Question 10

reduction is:

Answer 10

gain of electrons, sometimes also protons

Question 11

reduction potential

Answer 11

measures affinity for e-

-electrons move from lower E to higher E

Question 12

How to calculate net potential?

Answer 12

Enet=Ereduction - Eoxidation

Question 13

the ____ ring is derived from riboflavin

Answer 13

isoalloxazine (FAD)

Question 14

every NADH molecule = ___ ATP; every FADH2 = ___ ATP

Answer 14

2.5; 1.5