Gluconeogenesis

Question 1

what are the inhibitors of fructose 1-6–>fructose 6 phosphate?

Answer 1

F-2,6-BP and AMP

Question 2

what is the activator of fructose 1-6–>F 6 P?

Answer 2

Citrate

Question 3

How many ATP equivalents are necessary to perform gluconeogenesis?

Answer 3

11

Question 4

The Cori Cycle

Answer 4

lactate produced in muscle–>glucose–>glycolysis–>lactate

Question 5

the major site of gluconeogenesis is in the ___ but can occur in the ___

Answer 5

liver; kidney

Question 6

precursors to synth of glucose include _______

Answer 6

lactate, pyruvate, glycerol, a.a

Question 7

in microo-organisms, ________ are converted to glucose

Answer 7

acetate, lactate, propionate

Question 8

plants convert stored fats/proteins into __

Answer 8

sucrose

Question 9

pyruvate carboxylase adds a carbon dioxide to ____ to form ____, which happens in the ___

Answer 9

pyruvate; oxaloacetate; mitochondria

Question 10

what kind of prosthetic group does pyruvate carboxylase have? What else does it require?

Answer 10

biotin; ATP and Acetyl CoA

Question 11

PEP carboxykinase in the cytosol acts on ___ to form PEP through ____ and _____

Answer 11

oxaloacetate; phosphorylation and decarboxylation

Question 12

PEP carboxykinase inhibitors/activators:

Answer 12

none

Question 13

oxaloacetate has to be converted to ____ to get across the membrane

Answer 13

malate

Question 14

malate dehydrogenase produces NADH required for ______

Answer 14

glyceraldehyde dehydrogenase

Question 15

pyruvate can be formed from ___ by ____

Answer 15

lactate; lactate dehydrogenase

Question 16

glycerol can be converted to _____ with glycerol kinase and __________

Answer 16

DHAP; glycerol phosphate dehydrogenase