Test Three Flashcards
What is the normal blood volume in adults?
5 L
How does blood move through vessels?
Bulk flow
What happens when aortic pressure excedes that of the ventricle?
The aortic semilunar valve closes
When does the aortic semilunar valve open?
When left vent pressure exceeds aortic
What causes S1 and S2?
S1: closing of the AV valves
S2: closing of the SL valves
Which semilunar valve is most anterior?
Pulmonary valve
What causes mechanical events in the heart?
Electrical events- SA and AV node actionpotentials
What is a syncytium?
Fibers of the ventricles and separately fibers of the atria are functionally connected to rapidly spread action potentials
How does deoplarization occur in the SA node?
Gradually, after an AP the membrane potential returns o resting and gradually starts to depolarize again
What is a pacemaker potential due to?
Leakiness of sodium and other ions
All cardiac muscle cells are excited at the rate of the ____.
fastest one
What is an ectopic pacemaker?
When the pacemaker is not located in the SA node, another part of the heart develops a rhythm faster than the SA node
T or F: The atria contract at different times?
False the atria contract at relatively the same time, the AP spreads via gap junctions
How does an AP travel down to ventricles?
The SA node signal reaches AV node and it spreads through the AV buncle (bundle of his), through the left and right bundle branches to purkinjie fibers. The AV node is responsible for the delay in contraction between atria and ventricle.
P wave?
depolarization of atria
QRS Complex?
Deoplarization of the ventricles
T wave?
Repolariztion of ventricles
EKG’s record what kind of potential difference?
Extracellular recordings of leaking currents through the ECF from cardiac cells depolarizing or repolarizing
PR interval?
“pause” between depolarization of atria and the ventricles
QT interval?
Time during ventricular contraction where they are generating force
What is second degree heart block?
Skipped ventricular depolarization, no QRS complex,
What is third degree heart block?
QRS and P waves are are off beat
What causes the initial rising phase of an AP
sodium ions
The initial deoplarization causes what kind of channels to open and where?
Slow voltage gated calcium channels in the t tubules which results in plateau of depolariztion
Does intracellular calcium or extracellular calcium bind to troponin?
Intracellular, extracellular calcium causes the release of calcium from the sarcoplasmic reticulum
What muscle has a longer refractory period, skeletal or cardiac?
cardiac
How does premature ventricular contraction occur?
If the ventricle fires before the SA node, but after the refractory period. This could cause the SA node to fire during the refractory period resulting in no contraction