Test 5: The Platelet and Primary Hemostasis COPY Flashcards

1
Q

Is the process that maintains flowing blood in a fluid state and prevents loss of blood from sites of vascular injury.

A

Hemostasis

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2
Q

Normal hemostasis is dependent upon…

A

-integrity of vascular wall
- Platelets
-Coagulation system
-fibrinolytic system 

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3
Q

What are the stages of hemostasis?

A

-primary Hemostasis (Formation of platelet plug)
-Secondary hemostasis (Incorporation of fibrin and coagulation factors to form the secondary hemostatic plug (fibrin clot)
-fibrinolysis (Break down and removal of clot formed) 

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4
Q

Primary hemostasis consists of what two key parts?

A

-The vascular system
-Platelets

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5
Q

Vascular system consists of three types of blood vessels: 

A

-arteries and arterioles
-veins and Venules
-capillaries

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6
Q

______________ provides a smooth barrier between circulating blood and body tissues

A

Vascular intima

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7
Q

Vascular intima:

The innermost lining is a ___________ of endothelial cells.

A

Monolayer

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8
Q

Capillaries consist of a layer of endothelial cells on a basement membrane and surrounded by __________ -No smooth muscle or fibroblasts 

A

Pericytes

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9
Q

Functions of the endothelial cells are supported by the surrounding __________ and smooth muscles cells.

A

Fibroblasts

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10
Q

 The vascular intima functions to promote….

A

Coagulation and anticoagulation

-When intact, the endothelial cells produce anticoagulant properties

-When damaged the endothelial cells produce pre-coagulant properties

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11
Q

 -The average diameter of platelets in the circulation is _____ Microns

A

2.5

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12
Q

The average number of platelets is…

A

140,000 to 450,000/ cmm 

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13
Q

Play the structure is divided into what three zones?

A

-peripheral
-Structural/Sol-gel
-Organelle zones 

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