Test 4 - Contraceptives (Josh) Flashcards
Which two hormones are released to stimulated ovulation?
What are they released by?
FSH (Follicle Stimulating Hormone)
LH (Leutenizing Hormone
Released by the hypothalamus
—- & —- trick the hypothalamus so that FSH & LH are not released
Progestin
Estrogens
Blocking FSH & LH does what?
1) Stop Ovulation
2) Thicken cervical mucous
3) Thin uterine lining
Classes of Contraceptives:
- Estrogen-Progestin Oral Contraceptives
- Progestin Oral Contraceptives
- Non-oral Contraceptives
Combo oral contraceptives are all a combination of what?
Estrogen & Progestin
What are other indications for Estrogen-Progestin Oral Contraceptives?
- Premenstrual Dysphoric Disorder (PMDD)
- Acne
What is PMDD?
Premenstrual Dysphoric Disorder
- it is PMS w/ depression
Why do you have inactive tablets on the fourth week?
Menstruation happens on that week
A/E of Estrogen-Progestin Oral Contraceptives:
- Nausea
- Breast Tenderness
- Spotting
- Weight gain (edema)
What is the worst case scenario adverse effect of E-P Oral Contraceptives?
Thromboembolism
- primarily caused by estrogen
- not as common today b/c the doses are lower
E-P Oral Contraceptives are contraindicated for whom?
- smokers > 35 years old
- history of thromboembolism
Drospirenone (4th-generation progestin) causes what adverse effect?
Hyperkalemia
- avoid ACE inhibitor, ARB, Spironolactione, K+ supplements
Progestin Oral Contraceptives do not do what?
DON’T stop ovulation
They do thicken cervical mucous and thin uterine lining
50% of people will STILL ovulate
Progestin Oral Contraceptives have which other uses?
- dysfunctional uterine bleeding
- amenorrhea
- infertility
Which class of Oral Contraceptives do NOT have an off week?
Progestin Oral Contraceptives