Test 3 Fatty Acid synthesis Flashcards

1
Q

where does fatty acid synthesis occur

A

in the cytoplasm

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2
Q

intermediates are linked to

A

acyl carrier proteins (ACP)

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3
Q

all the enzymes for synthesis are linked in a big complex called

A

fatty acid synthase

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4
Q

the activated donor of acetyl group is

A

malonyl-ACP

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5
Q

the reductant is

A

NADPH

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6
Q

elongation stops at carbon?

A

16

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7
Q

who is the transporter for beginning molecules to leave and enter mitochondria

A

citrate

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8
Q

what does acetyl-Coa condense with to form citrate

A

oxaloacetate

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9
Q

what enzyme is used to catalyze acetyl-CoA and oxaloacetate together

A

citrate synthase

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10
Q

what is the committing step #1 of fatty acid synthesis

A

acetyl CoA becoming malonyl CoA

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11
Q

what enzyme is used to make acetyl CoA become malonyl CoA

A

acetyl-CoA carboxylase

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12
Q

what enzyme is used to make acetyl and malonyl CoA become ACP

A

acetyl or malonyl transacylase

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13
Q

how many aa residues make up ACP

A

77

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14
Q

what are the reaction steps in fatty acid synthesis

A

condensation, reduction, dehydration, reduction

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15
Q

what is produced when citrate has left mitochondria and into cytoplasm

A

NADPH

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16
Q

how many units are in the fatty acid synthase complex

A

3

17
Q

if elongation of fatty acids beyond 16 carbons happens, where does it occur

A

ER

18
Q

how many carbons are added during elongation

A

2 carbons at a time

19
Q

who is the donor to the 2 carbons during elongation

A

malonyl-CoA