Basic concepts of Metabolism Flashcards
what are the two metabolic related activities
catabolism and anabolism
energy extraction is known as
catabolism
synthesis of macromolecules known as
anabolism
catabolism and anabolism are known as
intermediary metabolism
what is coupling reaction
thermodynamically unfavorable reactions can be driven by favorable rxn
unfavorable added to favorable to get negative delta G
what is the universal currency of free energy
ATP
why is ATP the best
electrostatic repulsion
resonance stabilization
increase in entropy
hydration stabilization
how is there an increase in entropy in ATP
more water molecules can interact with Pi and ADP than ATP
why is ATP hydration stabilization
more water molecules can interact with Pi and ADP than ATP alone rendering the reverse reaction unfavorable
where does energy come from besides ATP
oxidizing carbon sources (food)
what does oxidizing carbon source mean
transferring electrons from carbon source to final acceptor
what do aerobic use as final electron acceptor
oxygen
anaerobic organsims use what as final electron acceptor
other molecules
if the carbon is more reduced then what
more energy it releases
what are the two ways that oxidation of carbon can transfer electrons
phosphorylation and ion gradient
what are examples of activated carriers for fuel oxidation
NADH and FADH2
what are examples of activated carriers for reductive biosynthesis
NADPH
CoA
where are most of the common motifs / activated carriers derived from
vitamins
what are the five principles of metabolic processes
anabolism and catabolism
ATP is main energy currency
oxidation of carbon sources will generate ATP
there are few types of reactions that all metabolic processes use
metabolism is tightly regulated
