Basic concepts of Metabolism Flashcards

1
Q

what are the two metabolic related activities

A

catabolism and anabolism

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2
Q

energy extraction is known as

A

catabolism

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3
Q

synthesis of macromolecules known as

A

anabolism

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4
Q

catabolism and anabolism are known as

A

intermediary metabolism

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5
Q

what is coupling reaction

A

thermodynamically unfavorable reactions can be driven by favorable rxn
unfavorable added to favorable to get negative delta G

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6
Q

what is the universal currency of free energy

A

ATP

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7
Q

why is ATP the best

A

electrostatic repulsion
resonance stabilization
increase in entropy
hydration stabilization

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8
Q

how is there an increase in entropy in ATP

A

more water molecules can interact with Pi and ADP than ATP

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9
Q

why is ATP hydration stabilization

A

more water molecules can interact with Pi and ADP than ATP alone rendering the reverse reaction unfavorable

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10
Q

where does energy come from besides ATP

A

oxidizing carbon sources (food)

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11
Q

what does oxidizing carbon source mean

A

transferring electrons from carbon source to final acceptor

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12
Q

what do aerobic use as final electron acceptor

A

oxygen

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13
Q

anaerobic organsims use what as final electron acceptor

A

other molecules

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14
Q

if the carbon is more reduced then what

A

more energy it releases

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15
Q

what are the two ways that oxidation of carbon can transfer electrons

A

phosphorylation and ion gradient

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16
Q

what are examples of activated carriers for fuel oxidation

A

NADH and FADH2

17
Q

what are examples of activated carriers for reductive biosynthesis

A

NADPH

CoA

18
Q

where are most of the common motifs / activated carriers derived from

A

vitamins

19
Q

what are the five principles of metabolic processes

A

anabolism and catabolism
ATP is main energy currency
oxidation of carbon sources will generate ATP
there are few types of reactions that all metabolic processes use
metabolism is tightly regulated