Test 2: antibiotics Flashcards
infection depends on what 3 factors
quantity of bacteria
virulence of the inoculum
resistance of the patient
examples of endogenous infectious agents
normal flora of skin, GI, pulmonary, renal
refined clean
One in which the gastrointestinal, respiratory, or genitourinary tracts are not invaded
No inflammation is noted
Aseptic technique is maintained throughout the surgical procedure. The surgery must be elective and the wound closed primarily without drains.
clean vs refined clean
clean can have drain that exits away from primary incision
clean/contaminated
The gastrointestinal, respiratory, or genitourinary tract is entered under controlled conditions.
The spillage of contents or contamination is judged to be
minor. In studies of human patients, the infection rate is
3% - 11%.
contaminated
There is a major break in aseptic technique.
Acute, nonpurulent inflammation is present
There is gross spillage of acute viscus. Examples: fresh, open, traumatic wounds are included in this category. For humans, the risk of infection with this category of wound is 10%-17%.
dirty wound
Older traumatic wounds containing devitalized tissues.
Operations in which exudate or a perforated viscus is
encountered. The infection rate in humans is 27%-40%.
dose rate for systemic prophylaxis
single dose 30-60 mins before surgery
2nd dose if surgery > 3 hours
stop after 24 hrs
what type of wound should you use systemic antibiotics for
clean contaminated and contaminated surgical wounds
when to use systemic antibiotics
Clean contaminated and contaminated surgical wounds
Clean surgical procedures involving an implant or prosthesis
Occurrence of an infection might be life-threatening
High-risk patient (immunocompromised)
cardinal signs of wound infection
discharge
dehiscence
depression
anorexia
+/- fever
E coli looks and smells like
serous to purulent
fecal smell
Strep looks and smells like
water exudate
no smell
Staph looks and smells like
thick and purulent
no smell
Pseudomonas looks and smells like
greenish blue
sweet musky smell
Anaerobic bacteria looks and smells like
found smelling- sulfur
cryo causes death by
direct and indirect injury
how does indirect cryo injury work
causes anoxia and death
attacks endothelial tissue, cause leakiness and clotting which cuts off blood supply
vascular stasis (capillary level)
direct cryo injury is by
ice crystal form inside cells and cause damage- thermal shock and apoptosis
overwhelming cellular pathology
— part of the cell are most susceptible to rapid freezing
mitochondria
recrystallization
small crystals form into bigger crystals during second rapid cooling phase
cytoskeletal disassembly occurs during
hypothermia
hyper or hypo osmolarity during frozen state?
hyper
monopolar or bipolar use ground plate
monopolar
when to use bipolar
plastic and neurosurgical
areas where you want to limit injury to surrounding tissues
benefits of elctrocautery
saves time
decreased blood loss
arteries up to 1 mm
veins up to 2 mm