Test 1: Lecture 1 fracture classifications Flashcards
— bone is highly dense and acellular
cortical/compact
— part of the bone is used for graphing
trabecular/spongy
porous
— hold the periosteum onto the bone
sharpey’s fibers
bone is made of
organic:
95% type 1 collagen
5% ground substance: proteoglycan and glycosaminoglycans
inorganic: hydroxyapatite (made by osteoblasts)
— cells cover bone surface and form organic matric osteoid
osteoblasts
(make bones)
— are osteoblasts that are incorporated into osteoid
osteocytes
connect to eachother
— are mutinucleated cell involved in bone resorption
osteoclasts
hydroxyapatite is made by — as unmineralized osteoid. It is then mineralized via —
osteoblasts
alkaline phosphatase
layers of the growth plate
zone of cartilage
zone of proliferation
zone of hypertrophy
zone of calcification
what part of the growth plate gets the most fractures
zone of hypertrophy
cells line up in columns, not as strong
what are some functions of bone
Protection
* Shape
* Blood cell production
* Mineral and fat storage
* Movement
* Acid-base balanc
bone elements develop within cell —
condensations
mesenchymal stem cells that differentiate into osteoprogenitor cells
two type of ossification
intramembranous (IO)- no cartilage
endochondral(EO)- cartilage intermediate
How does IO work?
Generally flat bones of the skull
Osteoprogenitor cells in cell condensation = osteoblasts
Osteoblasts produce bone matrix
Bony spicules form and fuse together to produce trabeculae
Trabeculae unite to form spongy bone
OP cells in spongy area produce marrow & in surrounding area produce periosteum
Osteoblasts of periosteum produce compact bone
how does EO work?
cartilage precursor
OP cells give rise to chondrocytes
Growth of cartilaginous bone-to-be by dividing chondrocytes
Primary center of ossification - forms before or after birth
Secondary center of ossification - forms after birth & forms epiphyses of long bones
Formation of articular cartilage and epiphyseal plate or growth/physeal plate
— are channels in osteon that allow connection between osteocytes
canaliculi
— canal runs down an osteon
— canal runs across an osteon
haversian
volkmann