Term Admisssions Flashcards

1
Q

What are the categories of term admissions?

A
  • Sepsis
  • Respiratory problems
  • Cardiac problems
  • Hypoglycaemia
  • Hypothermia
  • Jaundice
  • Birth asphyxia
  • Surgical problems
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2
Q

What are the symptoms of sepsis in a neonate?

A
  • Baby pyrexia or hypothermia
  • Poor feeding
  • Lethargy
  • Early jaundice
  • Hypoglycaemia
  • Hyperglycaemia
  • Asymptomatic
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3
Q

What are the risk factors for sepsis in neonates?

A
  • Premature rupture of membranes
  • Maternal pyrexia
  • Maternal GBS carriage
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4
Q

How is presumed sepsis managed?

A

-Admit NNU
-Partial septic screen (FBC, CRP, blood cultures) and blood gas
-Consider CXR, LP
IV penicillin and gentamicin 1st line
-2nd line iv vancomycin and gentamicin
-Add metronidazole if surgical/abdominal concerns
-Fluid management and treat acidosis
-Monitor vital signs and support respiratory and cardiovascular systems as required

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5
Q

What are the commonest organisms implicated in neonatal sepsis?

A
  • Group B streptococci
  • E.coli
  • Listeria
  • Coagulase negative staphylococci (if lines in situ)
  • Haemophilus influenzae
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6
Q

When does group B streptococcus sepsis occur?

A
  • Early onset – birth to 1 week

- Late onset or recurrence – up to 3 months

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7
Q

How may babies with GBS sepsis present?

A

Non-specific symptoms

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8
Q

What are the possible complications of GBS sepsis?

A
  • Meningitis
  • DIC
  • Pneumonia
  • Respiratory collapse
  • Hypotension
  • Shock
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9
Q

What is the prognosis of GBS sepsis?

A

4 to 30% mortality

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10
Q

What may congenital infection result in?

A
  • IUGR
  • Brain calcifications
  • Neurodevelopmental delay
  • Visual impairment
  • Recurrent infections
  • Other
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11
Q

Give examples of congenital infections.

A
  • Toxoplasmosis
  • Rubella
  • Cytomegalovirus
  • Herpes
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12
Q

What may cause respiratory distress?

A
  • Sepsis
  • Transient tachypnoea of the newborn
  • Meconium aspiration
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13
Q

How does transient tachypnoea of the new-born present?

A

Usually within the first few hours

  • Grunting
  • Tachypnoea
  • Oxygen requirement
  • Normal blood gases
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14
Q

What is the pathophysiology of transient tachypnoea of the new-born?

A

Delay in clearance of foetal lung fluids

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15
Q

What is the management of transient tachypnoea of the new-born?

A
  • Self-limiting and common
  • Supportive management
  • Antibiotics
  • Fluids
  • O2
  • Airway support
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16
Q

What is meconium aspiration?

A

Meconium is inhaled into the lungs

17
Q

What are the risk factors for meconium aspiration?

A
  • Post dates (aged placenta)
  • Maternal diabetes
  • Maternal hypertension
  • Difficult labour
18
Q

What are the symptoms of meconium aspiration?

A
  • Cyanosis
  • Increased work of breathing
  • Grunting
  • Apnoea
  • Floppiness
19
Q

How is meconium aspiration investigated?

A
  • Blood gas
  • Septic screen
  • CXR
20
Q

How is meconium aspiration treated?

A
  • Suction below cords
  • Airway support including intubation and ventilation
  • IV fluids and antibiotics
  • Surfactant
  • NO or ECMO
21
Q

What is the prognosis of meconium aspiration?

A
  • Most do well
  • Some develop PPHN
  • There is a associated mortality
22
Q

When does cyanosis occur?

A

Cyanosis occurs when there is more than 5g/dl of deoxyhaemoglobin

23
Q

How is the ‘blue baby’ investigated?

A
  • Examination and history
  • Sepsis screen
  • Blood gas and blood glucose
  • CXR
  • Pulse oximetry
  • ECG
  • ECHO
  • Hyperoxia test
24
Q

What is the differential cardiac diagnosis for the blue baby?

A
  • Transposition of the great arteries
  • Teratology of fallots
  • TAPVD
  • Hypoplastic left heart syndrome
  • Tricuspid atresia
  • Truncus arteriosus
  • Pulmonary atresia
25
What is the treatment for hypoglycaemia?
- If requires admission to NNU may still manage with enteral feeds - Monitor blood glucose - Start iv 10% glucose - Increase fluids - Increase glucose concentration (central iv access) - Glucagon - Hydrocortisone
26
How should hypothermia be managed?
- If unable to maintain temperature on PNW admit and place in incubator - Sepsis screen and antibiotics - Consider checking thyroid function - Monitor blood glucose
27
What may sever jaundice require?
- In severe jaundice may require admission for intensive phototherapy and/or exchange transfusion - Incubator and IV fluids may also be required
28
What is birth asphyxia?
Lack of oxygen at or around the birth which leads to multi-organ dysfunction
29
What are the causes if birth asphyxia?
- Placental problem - Long, difficult delivery - Umbilical cord prolapse - Infection - Neonatal airway problem - Neonatal anaemia
30
What is the first stage of birth asphyxia?
- Occurs within minutes without O2 | - Cell damage occurs with lack of blood flow and O2
31
What is the second stage of birth asphyxia?
- Reperfusion injury - Can last days or weeks - Toxins are released from damaged cells
32
What are the degrees of hypoxic ischaemic encephalopathy?
- Mild - Moderate - Severe
33
How is birth asphyxia managed?
- Supportive - Fluid restriction (avoid cerebral oedema) - Monitor for renal and liver failure - -Respiratory support - Cardiac support - Treat seizures - Therapeutic hypothermia (cooling): improves outcomes especially in the moderate group
34
What surgical problems may babies be admitted with?
- Oesophageal atresia/fistula - Duodenal atresia and other GI atresias - Causes of failure to pass stool - Abdominal wall defects - Diaphragmatic hernia
35
What causes of failure to pass stool are there?
- Constipation - Large bowel atresia - Imperforate anus +/- fistula - Hirschsprungs disease - Meconium ileus (think CF)
36
What abdominal wall defects can occur?
- Exomphalos | - Gastroschisis
37
What is the epidemiology of diaphragmatic hernias?
- 1 in 2500 births - 90% on left - M>F - Can be syndromic
38
How are diaphragmatic hernias managed?
- Intubation at birth - Respiratory support - Surgery - (ECMO)
39
What do diaphragmatic hernias usually present with?
Pulmonary hypoplasia