Dermatology Flashcards

1
Q

What is the most common type of exzema?

A

Atopic excema

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2
Q

What is atopy?

A

overactive immune response to environmental stimuli

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3
Q

What is the atopic march?

A

tendency to 3 commonly linked conditions:

ECZEMA, ASTHMA and HAYFEVER

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4
Q

Atopic exzema is caused by an abnormality in the expression of which protein?

A

Abnormality in filaggrin expression.

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5
Q

Distribution of atopic exzema

A
  • Infancy
    • Typically starts on the face/neck (cheeks common), can spread more generally
  • Older children
    • Flexural pattern predominates (antecubital fossae, popliteal fossae, wrists, hands, ankles)
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6
Q

Childhood exzema flares can be associated with:

A
  • Infections/viral illness
  • Environment: central heating, cold air
  • Pets: if sensitised/allergic
  • Teething
  • Stress
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7
Q

What type of exzema is this?

Which parts of the body does it affect?

What age group does it affect?

Treatment

A
  • Seborrheoic dermatitis
  • Mainly scalp and face
  • Often babies under 3 months, usually resolves by 12 months
  • Emollients, antifungal creams, antifungal shampoos, mild topical steroids
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8
Q

What type of exzema is this?

A
  • Discoid exzema
  • Scattered annular/circular patches of itchy eczema
  • Can occur in this pattern as part of atopic eczema or in isolation
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9
Q

What type of exzema is this?

Which body part is it found on?

Characteristics

A
  • Pomphylx eczema
  • Hand and foot exzema
  • Characterised by vesicles; can be intensly itchy
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10
Q

What are the two types of exogenous exzema?

A
  • Allergic eczema
    • sensitised to allergen
    • Type IV hypersensitivity - patch testing helpful
  • Irritant eczema
    • repeated contact; water and soaps, touching irritant foods; citrus, tomatoes, chemical irritants
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11
Q

Symptoms of immediate reactions from food allergy

A
  • lip swelling
  • facial redness/itching
  • anaphylactoid symptoms

(Type 1 reaction)

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12
Q

Symptoms of late reactions to food allergy

A
  • worsening of eczema 24/48 hours after ingestion
  • GI problems
  • Failure to thrive
  • Severe eczema unresponsive to treatment
  • Severe generalised itching - even when the skin appears clear

(Type 4 hypersensitivity)

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13
Q

Tests for immediate reaction food allergies

A
  • Blood test for specific IgE antibodies (RAST)
  • Skin prick testing
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14
Q

What are some of the causes of immediate reaction allergies

A
  • Commonest: milk, soy, peanuts, eggs
  • Airborne allergens - house dust mite, pet dander, pollens
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15
Q

How would you confrim the allergy for late reaction food allergies?

A
  • Dietary restrictions/eliminations 6-8 weeks
  • Eliminate one food at a time
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16
Q

Exzema treatment

A
  • Emollients
  • Topical steroids
  • Calcineurin inhibitors (e.g protopic – steroid sparing topical agents)
  • UVB light therapy
  • Immunosuppressive medication
17
Q

Side effects of prolonged use of topical steroids

A

Skin thinning

18
Q

How are creams measured?

A

Finger tip unit

19
Q

What type of skin infection is this?

How does transmission take place?

Describe the lesions

How long does it take to clear?

Management

A
  • Molluscum contagiosum
  • Transmission to close direct contacts
  • Pearly papules, umbilicated centre
  • Can take up to 24 months to clear
  • Reassurance + 5% Potassium Hydroxide
20
Q

What is this skin infection?

Which bacteria is this superficial skin infection caused by?

Describe the skin

Treatment

A
  • Impetigo
  • Staph aureus
  • Pustules and honey-coloured crusted erosions
  • Topical antibacterial (fucidin); Oral antibiotic (flucloxacillin)
21
Q

What is this skin condition?

What is it caused by?

How is it transmitted?

Treatment

A
  • Viral warts
  • Human papiloma virus
  • Transmitted by direct skin contact
  • Topical treatments such as salicylic acid and paring; Cryotherapy
22
Q

What does this picture show?

What is the most common cause for this in children?

A

Chicken pox

23
Q

What are the symptoms of varicella zoster?

A
  • Red papules (small bumps) progressing to vesicles (blisters) often start on the trunk
  • Itchy
  • Associated with viral symptoms
24
Q

When is varicella zoster contageous?

A

Contagious 1-2 days before rash appears and until lesions have crusted.

25
Q

What is this picture showing?

Describe the lesions

What areas does this occur?

How long does it take to resolve?

A
  • Erythema Nodosum
  • Painful, erythematous subcutaneous nodules
  • Over Shins; sometimes other sites
  • Slow resolution - like bruise, 6-8 weeks
26
Q

Causes of erythema nodosum

A
  • Infections - Streptococcus, Upper respiratory tract
  • Inflammatory bowel disease
  • Sarcoidosis
  • Drugs - OCP, Sulphonamides, Penicillin
  • Mycobacterial infections
  • Idiopathic
27
Q

What does this picture show?

What can cause this?

Treatment

A
  • Wheals / hives
  • Viral infection; bacterial infection; food or drug allergy; NSAIDS, opiates; vaccinations
  • Antihistamines 3x daily