Constipation and IBD Flashcards
What is constipation?
Infrequent passage of stool
What do you want to know about the child presenting with constipation?
- How often?
- How hard?
- Is it painful?
- Has there been a change?
What is normal stool frequency?
4 per day to 1 per week
What does stool frequency depend on?
- Age
- Diet
What are the components of the Bristol stool chart?
- Type 1 = separate hard lumps
- Type 2 = lumpy and sausage like
- Type 3 = sausage shape with cracks in the surface
- Type 4 = like a smooth sausage or snake
- Type 5 = soft blobs with clear cut edges
- Type 6 = mushy consistency with ragged edges
- Type 7 = entirely liquid
What are some signs and symptoms of constipation?
- Poor appetite
- Irritable
- Lack of energy
- Abdominal pain or distension
- Withholding or straining
- Diarrhoea
Why do children become constipated?
- Social
- Poor diet (insufficient fluids, excess milk)
- Potty training or school toilets issue
- Physical
- Intercurrent illness
- Medications (opiates and Gaviscon)
- Family history
- Psychological (secondary)
- Organic
What is the vicious cycle of constipation?
- Large hard stool
- Leads to pain or anal fissure
- Child withholds stool
- Becomes constipated
How does overflow diarrhoea develop?
- Rectum tells them they need to go but the child clenches the external sphincter
- Stool continues to be dehydrated by bowel becoming harder
- Back passage begins to stretch and creates a mega rectum
- Soiling occurs when the mega rectum holds the internal sphincter open
Social treatment of constipation
- Explain treatment to parents
- Dietary
- Increase fibre
- Increase fruit
- Increase vegetables
- Increase fluids
- Decrease milk
Psychological treatment of constipation
- Reduce the aversive factors by making going to the toilet a pleasant experience
- Correct height
- Not cold
- School toilets
- Avoid punitive behaviour from parents
- Reward good behaviour
- General praise and star charts
- Encourage child to try going to the bathroom after every meal
Medical treatment for constipation
- Soften stool and stimulate defecation
- Osmotic laxatives (lactulose)
- Stimulant laxatives (senna, picolax)
- Isotonic laxatives (movicol)
How is impaction treated?
- Empty impacted rectum
- Empty colon
- Maintain regular stool passage
- Slow weaning off treatment
How can constipation be confirmed on imaging?
- Colonic marker study
- When x-rayed at the end of the week the markers should have already be excreted.
- In constipation the markers can be seen in the rectum and distal colon
How has the incidence of Crohn’s disease changed in Scottish children?
Dramatic increase
What history and examination is required when diagnosing IBD?
- Intestinal symptoms
- Extra-intestinal manifestations (can include erythema nodosum)
- Exclude infection (negative stool culture with 2/52 history)
- Family History
- Growth and sexual development (growth chart plotting and Tanner staging)
What laboratory investigations should be carried out for IBD?
- Full blood count & ESR
- Anaemia
- Thrombocytosis
- Raised ESR
- Biochemistry
- Stool calprotectin
- Raised CRP
- Low Albumin
- Microbiology
- No stool pathogens
How does Crohn’s usually present in children?
- Lack of specific symptoms (present with weight loss and growth failure)
- Abnormal blood tests and high calprotectin
How does UC usually present in children?
- Symptomatic with bloody diarrhoea
- Do not necessarily have abnormal growth or blood tests
- High calprotectin
What are the definitive investigations for IBD?
- Radiological
- MRI (usually >5 years due to the need to keep still without a GA)
- Barium meal and follow through (younger kids)
- Endoscopy
- Colonoscopy
- Upper GI endoscopy
- Mucosal biopsy
- Capsule endoscopy
What are the aims of treatment in IBD?
- Induce and maintain remission
- Correct nutritional deficiencies
- Maintain normal growth and development
What are the treatments for IBD in children?
- Medical
- Anti-inflammatory
- Immuno-suppressive
- Biologicals (Infliximab)
- Nutritional
- Immune modulation
- Nutritional supplementation
- Liquid diet (Crohns)
- Surgical
- Currative in UC
- Not currative in Crohns