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Pharmacology > TC4-F Chemotherapies > Flashcards

TC4-F Chemotherapies Flashcards

1
Q

Doxorubicin

A

Anti-topoisomerase chemotherapeutic (“anthracycline”–antibiotic)

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2
Q

Bleomycin

A

Anti-topoisomerase chemotherapeutic (DNA-cleaving antibiotic)
- Isolated from Streptococcus verticillus

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3
Q

6-Mercaptopurine

A

Purine analog (chemotherapeutic)

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4
Q

Cyclophosphamide

A

Alkylating chemotherapeutic (nitrogen mustard)

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5
Q

IrinoTECan

A

Anti-topoisomerase I chemotherapeutic

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6
Q

Leuprolide

A

GRH analog (chemotherapeutic)

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7
Q

Carmustine

A

Alkylating chemotherapeutic (nitrosourea)

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8
Q

Palbociclib

A

CDK4, CDK6 inhibiting chemotherapeutic

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9
Q

ETOPOside

A

Anti-topoisomerase II chemotherapeutic (epipodophyllotoxin)

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10
Q

Imatinib Mesylate

A

Monoclonal antibody chemotherapeutic (BCR-ABL, “Gleevec”)

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11
Q

Atezolizumab

A

Monoclonal antibody chemotherapeutic (anti-PD1)

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12
Q

Trastuzumab

A

Monoclonal antibody chemotherapeutic (targeted at ErbB2)

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13
Q

Tamoxifen

A

Competitive inhibitor of estrogen (chemotherapeutic)

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14
Q

5-Fluorouracil

A

Pyrimidine analog (chemotherapeutic)

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15
Q

Gemcitabine

A

Pyrimidine analog (chemotherapeutic)

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16
Q

HydRoxyuRea

A

Ribonucleotide reductase inhibitor (chemotherapeutic)

17
Q

VemuRAFeniB

A

BRAF inhibiting chemotherapeutic

18
Q

Procarbazine

A

Alkylating chemotherapeutic

19
Q

Bortezomib

A

Signal pathway disrupting chemotherapeutic (binds 20S core of 26S proteasome)

20
Q

PacliTAXel

A

Anti-microtubule chemotherapeutic (taxane, disordered microtubule formation)

21
Q

Mitomycin C

A

Alkylating chemotherapeutic

- Isolated from Streptococcus caespitosus

22
Q

Trametinib

A

Steroid hormone antagonist chemotherapeutic

23
Q

Methotrexate

A

Dihydrofolate reductase inhibitor (chemotherapeutic)

24
Q

Cisplatin

A

Alkylating chemotherapeutic (Pt-coordination complex)

25
Q

L-asparaginase

A

Asparagine hydrolyzer (chemotherapeutic)

26
Q

Letrozole

A

Aromatase inhibitor (chemotherapeutic)

27
Q

ICI183780, “Fulvestrant”

A

Pure estrogen antagonist (chemotherapeutic)

28
Q

Vincristine

A

Anti-microtubule chemotherapeutic (binds tubulin)

Pharmacology (33 decks)

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