TBL on LFTs

Question 1

What is Jaundice

Answer 1

Yellowing of the slcera
Clinically apparent hyperbilirubinemia
Bilirubin normal range is <17
Bilirubin is clinically detectable >40

Question 2

What is liver failure

Answer 2

Ascites
Encephalopathy
Abnormalities of bilirubin and prothrombin time

Question 3

What is chronic liver disease

Answer 3

Insult to the liver that damages it for more than 6 months

Question 4

What are liver FUNCTION tests

Answer 4

Bilirubin
Albumin
Prothrombin

Question 5

What are liver DAMAGE tests

Answer 5

Alkaline phophatase
Alane amino transferase
Gamma glutamyl transferase GGT
All released in response to liver damage

Question 6

What are cholestatic LFTs

Answer 6

Used if they thing cause might be biliary
Alkaline phosphatase
GGT

Question 7

What are hepatic or hepatocellular LFTs

Answer 7

Alanine amino transferase

enzyme component of hepatocytes released when hepatocytes die

Question 8

Hepatic/hepatocellular damages causes

Answer 8

Increased ALT/AST

Alk phos/GGT near normal

Question 9

Whats the liver screen

Answer 9

FBC
U&Es 
Clotting 
LFTs 
Liver immunology 
Serum selenium 
HBV & HCV serology 
Alpha-anti trypsin

Question 10

What to do if patient has dilated bile duct

Answer 10

ECRP

endoscopic retrograde cholangio pancreatography

Question 11

What are LFTs with a mixed cause

Answer 11

All increases the same no. of times of the upper limit of normal