TB Drugs

Question 1

4 TB Drugs

Answer 1

RIPE
Rifampin
Isoniazid
Pyrazinamide (not on NBEO)
Ethambutol

Question 2

Rifampin

Answer 2

-prevents mRNA synthesis by binding to RNA polymerase
-Hepatotoxicity (liver damage)
-orange/pink urine and tears

Question 3

Isoniazid

Answer 3

-inhibits mycotic acid synthesis
-Hepatotoxicity and B6 deficiency
-Optic Neuritis (rare)

Question 4

Ethambutol

Answer 4

-inhibits mycobacterial cell wall synthesis by inhibiting arabinosyl transferase
-Optic Neuritis: retrobulbar and bilateral (most common)