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NBEO General Pharm > Autonomic/Neuromuscular Junction Drugs > Flashcards

Autonomic/Neuromuscular Junction Drugs Flashcards

1
Q

Parasympathetic

A

Cholinergic Receptors (muscarinic)
-bronchoconstriction, mitosis, rest and digest
-SLUD: salivation, lacrimation, urination, defecation

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2
Q

Sympathetic

A

Adrenergic Receptors (alpha and beta)
-bronchodilation, mydriasis, fight or flight
-decrease in secretions

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3
Q

Cholinergic Agonist

A

parasympathetic
-Direct: Pilocarpine, acetylcholine, bethanechol, carbachol
-Indirect: edrophonium, echothiophate, pyridostigmine, neostigmine

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4
Q

Cholinergic Antagonist

A

sympathetic
anti-anti-anti
Ocular: STop ACH

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5
Q

Donepezil

A

acetylcholinesterase inhibitor (indirect cholinergic agonist)
-indicated for the treatment of Alzheimer dementia

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6
Q

1st Generation H1 Blockers

A

Benadryl, brompheniramine, chlorpheniramine, promethazine

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7
Q

Antipsychotics

A

phenothiazines
-chlorpromazine, thioridazine

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8
Q

Antidepressants

A

TCAs: Elavil, Tofranil
MAOIs: Nardil

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9
Q

Muscle Relaxant

A

cyclobenzaprine (Flexeril)

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10
Q

Anxiolytic

A

diazepam (Valium)

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11
Q

Ipratropium (Atrovent)

A

MOA: muscarinic blockade (bronchodilation)

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12
Q

Adrenergic Agonist

A

sympathetic
-A2 and B1/B2 agonists
-increase aqueous humor production (glaucoma risk)

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13
Q

Alpha 2 Agonist

A

clonidine (Catapres)

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14
Q

Beta1/Beta2 agonist

A

isoproterenol (Isuprel)

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15
Q

Beta 2 agonists

A

salmetrol, albuterol, levabuterol. terbutaline. metaproterenol
-warning for glaucoma patients

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16
Q

Salmetrol

A

-only long acting Beta 2 agonist
-does not carry warning for glaucoma

17
Q

Dopamine Agonist Drugs

A

adrenergic agonist properties
(may cause angle closure glaucoma)
-bromocriptine
-ADHD drugs (Ritalin, Dexedrine)
-Parkinsons Drugs (Amantadine)

18
Q

Adrenergic Antagonist

A

parasympathetic
-A1 and B blockers

19
Q

Alpha 1 antagonist

A

-indicated for BPH
-tamsulosin (Flomax)
-terazosin
-prazosin

20
Q

Non-Selective Beta Blocker

A

labetolol, proranalol

21
Q

Beta 1 specific antagonist

A

atenolol, metoprolol

NBEO General Pharm (11 decks)

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