Antivirals Flashcards
Influenza Therapy
Tamiflu
-inhibits influenza A and B neuraminidase
-conjunctivitis reported in 1%
HIV Therapy
Retrovir
-inhibits reverse transcriptase
-bone marrow suppression/lactic acidosis/muscle breakdown
-amblyopia and macular edema
Hepatitis C Therapy
Ribavirin
-inhibits RNA polymerase
-combo with interferon
-Conjunctivitis (most common)
-RIBAViriN
RD
Ischemia (CWS)
Bleeding (retinal hemes)
A and V occlusions
optic Neuritis
Herpes Therapy
-inhibit DNA polymerase
-Herpes Simplex: Viroptic
-Herpes Zoster: Famciclovir/Acyclovir/Valacyclovir
-CMV: Zirgan (gancyclovir)/Foscarnet
Viroptic
-9x Day
-preserved w/ Thimerosal
Zirgan
-5x Day
preserved w/ BAK
Foscarnet (Foscavir)
-IV fot CMV and resistant HIV
-nephrotoxicity (kidney) and seizures