TB Flashcards
1
Q
What is latent TB?
A
Mycobacterium persist.
Granulomatous lesions calcify and become fibrotic (seen on CXR)
Patients are not infectious and are asymptomatic.
2
Q
What is miliary TB?
A
Widespread dissemination of Mycobacterium tuberculosis (see the image below) via hematogenous spread.
3
Q
How will Tb appear on histology?
A
Caseating granulomas, Acid- Fast Bacilli (AFB) smear
4
Q
What are the main 4 drug for TB treatment?
A
1) Rifampicin
2) Isoniazid
3) Pyrazinamide
4) Ethambutol
5
Q
What is mycobacterium tuberculosis?
A
Obligate aerobe small bacillus
Over 60% of cell wall is composed of lipids so CANNOT retain dye (neither gram positive or negative)
Very slow growth due to cell wall
