Soft tissue, bone, and joint infections Flashcards

1
Q

What are some defences of the skin?

A

1) Exfoliation –> sloughing of the stratum corneum dislodges many adherent bacteria
2) Dryness
3) Acidic pH (5.5)
4) Low temperature
5) Sweat glands
6) Normal bacterial flora –> Compete for sites and nutrients

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2
Q

Name some micro-organisms that are present on the skin….

A

1) S. epidermidis
2) S. aureus
3) Micrococci
4) Diphtheroids

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3
Q

What is Staphylococcus aureus?

A

Gram positive cocci and coagulase positive, golden colonies.

Acquired resistance to beta lactam antibiotics – MRSA

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4
Q

What is Streptococcus pyogenes?

A

Group A streptococci.
Gram positive cocci.
Beta haemolytic.
Colonises the pharynx.

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5
Q

What is impetigo?

A

Superficial infection

Friable golden crusts over erythematous skin

More common in children

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6
Q

What is folliculitis?

A

Infection of hair follicles.
Common sites are groin and scalp.
Caused by S.aureus.
Treatment is flucloxacillin.

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7
Q

What is furunculosis?

A

Deep inflammatory lesion progressing from a folliculitis.

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8
Q

What is a carbuncle?

A

A red, swollen, and painful cluster of furuncle that are connected to each other under the skin.

Extend into the subcutaneous layer, multiple abscesses develop, separated by connective tissue.

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9
Q

What is an acute paronchia?

A

Skin infection arising from an nail.

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10
Q

What is cellulitis?

A

An inflammatory condition of the lower dermis and subcutaneous tissue caused by bacterial infection.

Commonly caused by S.Aureus (CA-MRSA).

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11
Q

What is erysipelas?

A

Infection involving the upper dermis and extends into the superficial cutaneous lymphatics.

Tend to have raised red skin.

Group A streptococci is the most common cause.

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12
Q

What is a surgical site infection (SSI)?

A

Infections that affect the surgical wound or
deeper tissues handled during the surgical procedure
resulting in local signs and clinical symptoms.

Infection must occur within 30 days (or 1 year if an implant was inserted).

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13
Q

What is septic arthritis?

A

Infection of the joint spaces.

Most common in a joint affected by rheumatoid arthritis or history of trauma.

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14
Q

What are the 3 ways in which bacteria can enter a joint?

A

1) Haematogenous route – most important
2) Direct inoculation via trauma
3) Arthritis with associated tendonitis

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15
Q

What is osteomyelitis?

A

Infection of the bone.

Can be infected via trauma/surgery or by haematogenous route.

Treated with flucloxacillin (OR vancomycin if MRSA).

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16
Q

What are the most common dermatophyte agents for skin infections?

A

Trichophyton,

Epidermophyton, and Microsporum

17
Q

How are dermatophyte infections treated?

A

Topical imidazoles or other antifungal preparations

e.g. nystatin, canestan, clotrimazole