tablets ppt Flashcards

1
Q

sugar for palatability; adds 50% to tablet bulk

A

Sugar-Coated (CT)

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2
Q

broken and chewed before ingestion; mannitol (50% of tablet bulk); xylitol (sugar free)

A

Chewable (CT)

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3
Q

coated with a thin layer of a polymer
capable of forming a skinlike film; less bulky

A

Film-Coated (CT)

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4
Q

disintegrate in intestinal fluid; delayed release

A

Enteric-Coated (CT)

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5
Q

compressing the fill material more than once

A

Multiple Compressed Tablet

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6
Q

ex. Halazone tablets and KMnO4 tablets for solution

A

Tablets for Solution

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7
Q

compressed granular effervescent salts; Na bicarbonate + citric acid + tartaric acid

A

Effervescent Tablet

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8
Q

dissolved at the buccal/cheeks of the mouth

A

Buccal Tablet

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9
Q

dissolved under the tongue

A

Sublingual

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10
Q

aka Compounding Tablets; for extemporaneous compounding, never dispensed as Dosage Form

A

Dispensing Tablet (MT/TT)

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11
Q

no longer used because of the difficulty in achieving sterility

A

Hypodermic Tablets (MT/TT)

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12
Q

aka Vaginal inserts; bullet or ovoid shaped inserted for local or systemic effects

A

Vaginal Tablet (MT/TT)

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13
Q

designed to release their medication with no rate controlling features

A

Immediate Release

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14
Q

have drug release features based on time, course, and/or location

A

Modified Release

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15
Q

aka Controlled Release; release medication over an extended period

A

Extended Release

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16
Q

release at a time other than promptly after administration

A

Delayed Release

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17
Q

2 single doses, one for immediate, another for delayed

A

Repeat Action

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18
Q

directed towards a region, tissue, or site of absorption

A

Targeted Release

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19
Q

Contains one or more medicinal agents in a flavoured, sweetened base intended to dissolve slowly in the mouth

A

Lozenges

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20
Q

Sugar based lozenges on a stick and contain fentanyl citrate

A

Lollipops

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21
Q

Compressed lozenges; discoid shaped

A

Troches

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22
Q

Molded lozenges ;Softer and has a higher concentration of sugar or gelatin

A

Pastilles

23
Q

SDF other than suppositories for insertion to body orifices

A

Inserts

24
Q

Small, sterile SDF containing a concentrated drug for SC implantation where it continuously release the medication over long periods

A

Implants/Pellets

25
Q
  • consider compatibility with excipients
  • Excipients need compatible with the API
A

Active Pharmaceutical Ingredients

26
Q

Inert substance added to increase tablet size which is practical for

A

Diluent/Filler/Bulking Agent

27
Q

diluent compatible to nearly all except avid drugs

A

Lactose

28
Q

• Imparts cohesiveness to powders causing them to form granules.
• Mostly Sticky materials

A

Binder/Granulators

29
Q

•Facilitates the break up of the tablet when in contact with water/ fluid or in aqueous medium in the GIT.

A

Disintegrants

30
Q

• Newer class of disintegrants which are effective at much lower levels (2-4%)
• Alternative to traditional disintegrants
• Has large size

A

Superdisintegrants

31
Q

• Antifrictionals or Flow Activators (Stop the friction improve the flow properly)
• Hydrophobic powders added prior to compression to reduce friction and
improve flow properties

A

Compression Aids

32
Q

Facilitates ejection of tablet from die cavity

A

Lubricant

33
Q

reduces sticking to the punch or die

A

Anti-Adherent

34
Q

enhances flow of the granules

A

Glidants

35
Q

3 roles (glidant, antiadherent, lubricant) - most Common antifrictional

A

Mg stearate

36
Q

Acidic counterpart of Mg stearate

A

Stearic Acid

37
Q

Acidic counterpart of Mg stearate

A

Stearic Acid

38
Q

Water soluble colorants used as a solutions - Organic colorants
-FD & C

A

Dyes

39
Q

Water insoluble colorants that have been absorbed on Hydrous Oxide and used as Dry powders
- Use in topical preparations , cosmetics
-D & C

A

Lakes

40
Q

stores materials for compressing

A

Hopper

41
Q

distributes materials into dies

A

Feed Frame

42
Q

controls the size and shape of the tablet

A

Dies

43
Q

compacts materials within the dies (also controls shape)

A

Punches

44
Q

guide the punches

A

Cams

45
Q

tablet press that produces about 200 tabs per min

A

Single-punch press / Eccentric press

46
Q

tablet press that produces over 10,000 tabs per min

A

Rotary press/multi station press

47
Q

• First step in any manufacturing process
• weighing and measuring

A

Dispensing

48
Q

It is the unit operation in which the size of solid pieces of a material is reduced by the application of mechanical force.

A

Size Reduction

49
Q

Strain between two surfaces moving in opposite directions or one moving and one stationary producing shearing action.

Ex. Colloid Mill

A

Attrition

50
Q

• Strain is between two or more sharp edged surfaces.
• lt is used for fibrous materials as wood and paper

Ex. Cutter Mill

A

Cutting

51
Q

Equipment used in size reduction

A

Ball Mil
Hammer Mill

52
Q

opposes particle fracture and size reduction ceases. In some cases particle agglomeration occurs to such a degree that subsequent milling actually causes size enlargement.

A

Particle Agglomeration

53
Q

It is a process by which powder particles are removed from a fluid (gases or liquids).

A

Solid Separation