notes

Question 1

ensure all components will disolve

Answer 1

mixing

Question 2

improve odor and taste of the solution

Answer 2

mixing and storage

Question 3

examples of Dosage Forms that contain volatile oil

Answer 3

Aromatic water and spirits

Question 4

Solution transfer in one Filter medium

Answer 4

parallel

Question 5

transfer 2 or more flter medium
- ensure to prevent unremoved particles

Answer 5

Series

Question 6

Sterile
- 0.22 mcm
« even smallest bacteria cannot be filtered

Answer 6

Membrane Filter

Question 7

QC test to determine the membrane filter

Answer 7

Bubble point test

Question 8

a coliodal system in which the dispersed particies are solid

Answer 8

suspensoid

Question 9

filling used For viscous

Answer 9

gravimetric filling

Question 10

filling to maintain the level

Answer 10

constant level filling

Question 11

make sure suspension are suspended
In

Answer 11

suspensoid

Question 12

viscosity enhancer

Answer 12

suspending agent

Question 13

magnesium Aluminum silicate

Answer 13

veegum

Question 14

thixotropic agent
- not settle solid drug

Answer 14

bentonite magma

Question 15

displace air From crevices of hydrophobic solids to allow penetration of water

Answer 15

wetting agents

Question 16

sucrose in syrup coat to dispersed

Answer 16

syrup

Question 17

form flocculates
- prevent caking formation

Answer 17

flocculating agents

Question 18

made of stainless steel and jackered

Answer 18

mixing tanks

Question 19

most inert grade stainless steel

Answer 19

SS 316

Question 20

mixer with various impellers

Answer 20

mechanical stirrer

Question 21

For dispersion of suspensions

Answer 21

colloid mill

Question 22

-compresses w. high pressure emulsification
- ensure uniForm

Answer 22

homogenizer

Question 23

uses Ultrasonic energy,
- has limited output.

Answer 23

ultrasonifier

Question 24

added to maintain required pH

Answer 24

buffers

Question 25

especially in suspension and emusion
- to enhance the taste in surups

Answer 25

viscosity enhancer

Question 26

to prevent water loss in vanishing cream

Answer 26

humectants

Question 27

prevent degradation of drugs

Answer 27

stability enhancers

Question 28

prevent microbial growth

Answer 28

preservatives

Question 29

-alkyl oF p-hydroxybenzoic acid

• make compound enter the cell membrane In fungi
• cause lysis (not build)

Answer 29

Parabens

Question 30

-cause protein denaturation

Answer 30

benzyl alcohol

Question 31

Molds

Answer 31

methyl paraben

Question 32

yeast and bacteria

Answer 32

propyl paraben

Question 33

studies show that it can cause
endocrine disruptors (breast cancers)

Answer 33

long chain paraben (butyl paraben)

Question 34

prevent oxidation
- most common cause of degration oF drugs

Answer 34

antioxidants

Question 35

react with free radicals

Answer 35

true antioxidant

Question 36

BHT

Answer 36

butylated hydroxy toluene

Question 37

BHA

Answer 37

butylated hydroxy anisole

Question 38

they oxidized instead of component
OF skIn

Answer 38

reducing agents

Question 39

react w heavy metals
- react w neavy metal, same w free radicals, and heavy metal cause oxidation)
to prevent catalyst

Answer 39

antioxidant (synergist)

Question 40

Used of ointment roller mill to mix heat-sensitive ointment bases
- to ensure smooth texture
- to incorporate the API
- not used for heat
- used for lanolin

Answer 40

incorporation method

Question 41

• heat involved
• use of steam-jacketed kettles to melt anhydrous ointment bases and cooling gradually until congealed
• beeswax

Answer 41

fusion method

Question 42

the internal force in a liquid drop (promote dissociation of the molecule of the → substance / resisting distortion of the drop into a less Spherical form

Answer 42

surface tension theory