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DOSAGE > TABLETS > Flashcards

TABLETS Flashcards

1
Q

are solid pharmaceutical dosage form containing drug substances usually prepared by molding or compression with the aid of suitable excipients

A

TABLETS

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2
Q

tablets may vary in ____, ____, ____, ____, ____, ____, and ____ characteristics and in other aspects, depending on their intended use and method of manufacture

7

A

size
shape
weight
hardness
thickness
disintegration
dissolution

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3
Q
  • uncoated tablet manufactures by compression
  • with sufficient pressure forcing the powders or granules to make the desired shape
  • contained no special coating
A

COMPRESSED TABLETS

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4
Q

fillers designed to make up the desired bulk, flow properties and compression characteristics

EXAMPLES: lactose, mannitol starch, dibasic calcium phosphate, sorbi

A

DILUENT OR FILLERS

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5
Q

used to cause adhesion of powder particles in tablet granulations

acacia, carboxymethylcellulose, gelatin, pregelatinized starch

A

HINDERS OR ADHESIVES

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6
Q

promote disruption of solid mass into smaller particles

carboxymethylcellulose, starch, microcrytalline cellulose

A

DISINTEGRANTS

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7
Q

to improve the flow of the powdered mixture

colloidal silica, cornstarch, talc

A

GLIDANTS

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8
Q

prevent tablet ingredients from sitcking to punches and dies during production

magnesium stearate

A

ANTI-ADHERENT

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9
Q

reduce friction during tablet compression

Ca, Mg, Zn stearate, mineral oil, stearic acid

A

LUBRICANT

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10
Q

what type of excipient is the dibasic calcium phosphate (Ditab)?

A

DIRECT COMPRESSION EXCIPIENT

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11
Q

FD&C lakes are used as

A

COLORANT

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12
Q

colorant used in tablets

A

FD&C lake

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13
Q

flavoring agent and sweetening agent is added in ____ and ____ tablet

A

CHEWABLE
BUCCAL

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14
Q

substances capable of holding quantities of fluids in an apparently dry state

fused silica, bentonite, kaolin, magnesium carbonate, microcrystalline

A

ADSORBENTS

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15
Q

tablet coating that contains liquid glucose, sucrose

A

SUGAR-COATING AGENTS

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16
Q

sugar-coating agents

A

LIQUID GLUCOSE
SUCROSE

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17
Q

tablet coating that contains methylcellulose, ethylcellulose, hydroxy-ethyl cellulose, hydroxy propyl cellulose

A

FILM-COATING AGENTS

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18
Q

tablet coating that contains cellulose acetate phthalate, shellac (35% in alcohol, “pharmaceutical glaze”)

A

ENTERIC-COATING AGENTS

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19
Q

% of shellac in alcohol

A

35%

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20
Q

35% in alcohol
pharmaceutical glaze

A

SHELLAC

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21
Q

shellac is also known as

A

PHARMACEUTICAL GLAZE

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22
Q

prepare by subjecting the fill material to more than a single compression

A

MULTI-LAYERED TABLET

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23
Q
  • protects the enclosed drug from the environment and provides a barrier to objectionable taste or odor
  • DISADVANTAGE: 50% larger and heavier than the original uncoated tablet
A

SUGAR-COATED TABLET

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24
Q
  • coated with a thin layer of polymer capable of forming a skin-like film over the tablet
  • ADVANTAGES: more durable, less bulky, less time-consuming to apply
A

FILM-COATED TABLET

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25
Q

capsule shaped compressed tablet. more tamper-evident than unsealed capsules

A

GELATIN-COATED TABLET

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26
Q

has a delayed release feature and disintegrates in the small intestine

A

ENTERIC-COATED TABLET

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27
Q

where does the enteric-coated tablet disintegrates?

A

SMALL INTESTINE

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28
Q

gelatin-coated tablet is more tamper-evident than

A

UNSEALED CAPSULES

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29
Q

designed to disintegrate and release their medication with no specific rate-controlling features

A

IMMEDIATE RELEASE TABLET

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30
Q

designed to release their medication in a predetermined manner over an extended period

A

EXTENDED RELEASE TABLET

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31
Q

dissolves in the buccal pouch and it erode slowly

A

BUCCAL TABLET

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32
Q
  • dissolves beneath the tounge and it dissolved promptly and produce rapid effect
  • used in sudden pain (chest pain)
A

SUBLINGUAL TABLET

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33
Q
  • are especially useful for administration of large tablets to children and adults who have difficulty in swallowing
  • do not contain disintegrants
  • commonly used excipient: mannitol
A

CHEWABLE TABLET

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34
Q

commonly used excipient in chewable tablets

A

MANNITOL

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35
Q

common sweetener used in chewable tablet

A

MANNITOL

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36
Q

common sweetener used in sugar-free chewable tablets

A

XYLITOL

37
Q
  • disc-shaped, solid dosage forms containing medicinal agent and generally a flavoring substance in a hard candy or sugar base
  • they are intended to be dissolved slowly in the oral cavity for localized effects
  • made by compression or molding
  • candy type preparation
A

LOZENGES

38
Q

another term for lozenges

A

TROCHES

39
Q

lozenges in a gummy type preparation

A

PASTILLES

40
Q
  • disintegrating or dissolving in the mouth within 1 minute, some within 10 secs
  • designed for children & elderly who has difficulty in swallowing
  • liquefy in tounge and patient swallows
A

RAPID RELEASE TABLET

41
Q
  • also called vaginal inserts
  • uncoated, bullet-shaped or ovoid tablets inserted into the vagina for local effects
  • made by compression
  • a plastic inserter usually accompany the product
A

VAGINAL TABLET

42
Q

what usually accompanies vaginal inserts/tablets

A

PLASTIC INSERTER

43
Q
  • a small tablet that is prepared for insertion under the skin by giving a small surgical cut into the skin which is stitched after the insertion of tablets
  • the tablet must be sterile
  • do not contain excipients
  • contraceptive tablets
A

IMPLANTS

44
Q

prepared by compressing granular effervescent salt and releases carbon dioxide when in contact with water

A

EFFERVESCENT TABLET

45
Q
  • small, usually cylindrical molded or compressed tablet containing small amount of usually potent drugs
  • tablet is soft and soluble
  • has rapid effect
  • combination of sucrose + lactose
  • inserted in a capsule or dissolved in liquid to provide accurate amount of potent drug substances
  • prepared by molding method
A

MOLDED TABLETS / TABLET TRITURATES

46
Q

molded tablet is also known as

A

TABLET TRITURATES

47
Q

Molded tablets / tablet triturates are a combination of

A

sucrose + lactose

48
Q

sweetener used in molded tablet / tablet triturate

A

SUCROSE

49
Q

diluent used in molded tablet / tablet triturate

A

LACTOSE

50
Q

commonly used diluent in molded tabs

2

A

SUCROSE
LACTOSE

51
Q
  • used by doctors in extemporaneous preparation of parenteral solutions
  • tablets are dissolved in suitable vehicle, sterility is attained then injected
  • not used anymore because of sterility problem
A

HYPODERMIC TABLETS

52
Q
  • contains large amount of highly potent drug substances, pharmacists could rapidly obtain premeasured amounts of compounding multiple dosage units
  • no longer available
A

DISPENSING TABLETS

53
Q

dispensing tablets are also known as

A

COMPOUNDING TABLETS

54
Q

added in containers that is used to absorb moisture

A

DESSICANT PACKET

55
Q
  • a raspberry sugar-based lozenge on a stick containing fentanyl citrate
  • Actiq is the first product designed to aid in controlling breakthrough pain in cancer patients
  • immediate relief – its effect lasts for 15 mins
A

LOLLIPOPS

56
Q

lollipops contains

A

FENTANYL CITRATE

57
Q

lollipop

the first product designed to aid in controlling breakthrough pain in cancer patients

A

ACTIQ

58
Q

the effect of lollipops last for how many mins

A

15 mins

59
Q

first manufacture who produced lollipops

A

CEPHANOL

60
Q
  • small, solid particles of uniform shape sometimes called beads
  • may be given orally or parenterally
  • physical separation of incompatible substances
  • placed inside hard gelatin capsule
A

PELLETS

61
Q

pellets are sometimes called as

A

BEADS

62
Q
  • small, round, solid dosage forms containing a medicinal agent intended to be administered orally
  • prepared by a wet massing and molding technique
  • excipients are selected based on their ability to produce a firm and plastic mass
  • liquid excipients are added to bind and provide plasticity to the mass, which is formed by kneading
  • the firmness and plasticity are required for the mass to be worked and retain the produced shape
A

PILLS

63
Q

pills are prepared by

A

WET MASSING
MOLDING TECHNIQUE

64
Q

pills

are added to bind and provide plasticity to the mass, which is formed by kneading

A

LIQUID EXCIPIENTS

65
Q

PILLS

required for the mass to be worked and retain the produced shape

2

A

FIRMNESS
PLASTICITY

66
Q

allows the tablets to be easily break into two or more parts

A

SCORE, GROOVE

67
Q

add the necessary bulk to a formulation to prepare tablets of the desired size

A

DILUENT OR FILLERS

68
Q

promote adhesion of the particles of the formulation, allowing granulation to be prepared and maintaining the integrity of the final tablet

A

BINDERS OR ADHESIVES

69
Q

promote breakup of the tablets after administration to smaller particles for ready drug availabiltiy

A

DISINTEGRANTS

70
Q

inner tablet being the

A

CORE

71
Q

outer tablet being the

A

SHELL

72
Q

the coating of sugar coated tablets are

2

A

water soluble
quickly dissolves

73
Q

a tablet’s durability may be determined by

A

FRIABILATOR

74
Q

widely employed method for the production of compressed tablets

A

WET GRANULATION

75
Q

% of starch that is usually suitable

A

5% - 10%

76
Q

% of starch that may be used to promote more rapid tablet disintegration

A

20%

77
Q

METHOD

  • the powder mixture is compacted in large pieces and subsequently broken down or sized into granules
  • either active ingredient or the diluent must have cohesive properties
A

DRY GRANULATION METHOD

78
Q

may be used to increase the density of a powder

A

POWDER COMPACTORS

79
Q

about 70% as sweet as sucrose

A

MANNITOL

80
Q

a waterproofing substance

A

SHELLAC

81
Q

method used in hard tablets

A

COMPRESSION

82
Q

method used in soft tablets

A

MOLDING

83
Q

prevents friction

A

LUBRICANT

84
Q

large, usually elongated tablets intended for administration to large animals

A

BOLUS TABLETS

85
Q

PATIENT COUNSELING

what should not be done after taking a chewable tablet

A

do not drink water immediately

86
Q

PATIENT COUNSELING

Buccal tablets

A

30mins - 1hr after taking the tablet saka uminom ng water
rotate/alternate sides of the cheek

87
Q

PATIENT COUNSELING

ORALLY DISINTEGRATING TABLETS

A

do not take water immediately

88
Q

PATIENT COUNSELING

LOZENGES

A

bawal kagatin

DOSAGE (19 decks)

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