SOLUTIONS Flashcards
Are liquid preparations that contain one or more substances dissolved in water or co-solvent mixtures
SOLUTIONS
Another term of ethyl alcohol
ETHANOL
Chemical formula of ethyl alcohol
C2H5OH
Ethanol is the primary solvent used
ORGANIC
two uses of ethanol
SOLVENT
EXCIPIENT
Prepared by mixing equal volumes of Alcohol USP, and Purified water USP
DILUTED ALCOHOL NF
Contains 70% of ethyl alcohol by volume
RUBBING ALCOHOL
Clear syrupy liquid with a sweet taste, miscible both in water and in alcohol, and has a preservative qualities, and often used as a stabilizer and an auxiliary solvent in conjunction with water or alcohol
GLYCERIN USP
Another term for glycerin
GLYCEROL
70% by volume isopropyl alcohol; Externally as a rubefacient and soothing rub; as a vehicle for topical products
ISOPROPYL / RUBBING ALCOHOL
Ways on how to purify water
3
DISTILLATION
ION EXCHANGE TREATMENT
REVERSE OSMOSIS
Most expensive way to purify water
DISTILLATION
Heat is eliminated, generally passes water through a column of cation and anion exchangers consisting of water insoluble synthetic polymerized phenolic, carboxylic, amino or sulfonated resin of high molecular weight.
ION EXCHANGE METHOD
Membrane filtration; a pressurized stream of water is passed parallel to the inner side of a filter membrane core
REVERSE OSMOSIS
Commercially available; diluted the concentration of solution
ORAL SOLUTION
Dry powder for reconstitution prior to use; Contains all of the formulative components, including drug, flavorant, colorant, buffers, and others, EXCEPT FOR THE SOLVENT.
DRY POWDER MIXTURE
Expiry date of the product if not refrigerated
7 days
expiry date of the product if refrigerated
14 days
Solutions used for the treatment of diarrhea; available in liquid or powder packet for reconstitution
ORAL REHDYRATION SOLUTION
Contains sodium sulfate, sodium bicarbonate, sodium chloride, potassium chloride
PEG 3350 electrolyte solution
preparation for the bowel procedures
oral colonic lovage solution
Recommended dose of Peg ES
4L of the solution
Colorless to slightly yellow clear effervescent liquid having a sweet acidulous taste and a lemon flavor
MAGENSIUM CITRATE ORAL SOLUTION
Use of 27
SALINE CATHARTIC
Synonyms of 27
CITARTE OF MAGNESIA
Use of sodium, citrate and citric acid solution
SYSTEMIC ALKALINIZER
Are concentrated, aqueous preparations of a sugar or sugar substitutes with or without added flavoring agent and medicinal substances
SYRUP
Good vehicle for drugs requiring acid medium
CHERRY SYRUP
ORANGE SYRUP
Alcohol free vehicle for extemporaneous compounding of syrup
ORA-SWEET
ORA-SWEET SF
. Effectively masks bitter tasting drugs
COCOA SYRUP
Used to disguise salty or sour taste of drugs
RASPBERRY SYRUP
________% of syrup can act as preservatives
85% w/v, 65% w/w
Specific gravity of simple syrup
1.313
Are clear, sweetened, hydroalcoholic solutions intended for oral use, and are usually** flavored to their palatability**
ELIXIR
High alcoholic elixir contains ________% of alcohol
73 - 78%
Low alcoholic elixir contains ____% of alcohol
8 - 10%
Iso-alcoholic elixir contains ____% of alcohol
mix of high & low alcoholic elixirs
at how many percent of alcohol elixir is self-preserving
more than 10 - 12%
Are alcoholic or hydroalcoholic solutions of volatile substances
TINCTURE
Another term for spirits
ESSENCE
Are ALCOHOLIC OR HYDROALCOHOLIC solutions of VOLATILE substances
SPIRITS
Are CLEAR, SATURATED AQUEOUS SOLUTIONS OF VOLATILE OILS or other aromatic or volatile substances; Used for perfume and flavoring; Stored in a tight, light-resistant containers
AROMATIC WATER
Are alcoholic or hydroalcoholic solutions of chemicals or soluble constituents of vegetable drugs
TINCTURE
____% of strength for Belladonna tincture
10%
____% of strength for tolu balsam
20%
____% Sweet orange peel tincture
50%
A tincture that is used for treatment to diarrhea
PAREGORIC TINCTURE
camphorated opium tincture
Use of compound benzoin tincture
PROTECTANT
Use of iodine tincture
LOCAL ANTI-INFECTIVE
Used of thimerosal tincture
ANTISEPTIC
Alcoholic content of Opium Tincture
17 - 21%
Alcoholic content of Compound Benzoin Tincture
74 - 80%
Alcoholic content of Iodine Tincture
44 - 50%
Alcoholic content of Thimerosal Tincture
approx 50%
Extracts are commonly obtained from plants and they are also called
GALENICAL
They are referred to 100% tincture
FLUID EXTRACT
Known as Burow’s solution, an astringent wash or wet dressing, used in various types of dermatologic lotions, creams, and pastes
ALUMINUM ACETATE
Liquor Carbonis Detergens; Liquor Picis Carbonis; LCD
COAL TAR
Uses of coal tar topical solution
LOCAL ANTI-ECZEMATIC
The percentage of hydrogen peroxide solution
2.5 - 3.5%
It is a 4% (Hibiclins), used as a surgical scrub, hand wash, and skin wound and general skin cleanser
CHLORHEXIDINE GLUCONATE
A 10% solution employed as surgical scrub and nonirritating antiseptic solution
POVIDONE-IODINE SOLUTION
Merthiolate solution that is used as bacteriostatic and fungistatic
THIMEROSAL
Are clear, saturated aqueous solutions of volatile oils or other aromatic or volatile substances
AROMATIC WATER
Upon the Addition of electrolytes in medicated water it may result to ____ of the volatile ingredient
SEPARATION
Proper storage condition of aromatic water
TIGHT, LIGHT-RESISTANT BOTTLE
The process of redistillation two or more times until the distillate becomes clear.
COHOBATION DISTILLATION
Are solutions used to treat the pharynx and the nasopharynx by forcing air through the lungs through the gargle which is held in the throat
GARGLE
Another name of eye wash
COLLYRIUM
Another name of nasal wash
COLLUNARIUM
Are aqueous solutions directed against a part or into a cavity of the body
DOUCHE
two uses of douche
CLEANSING
ANTISEPTIC
How to administer a douche
with the use of bulb syringe
Another term for enema
CLYSTERS
Use for evacuation of bowel is termed as
ENEMA
Active ingredient of fleet enema
SODIUM PHOSPHATE
Another term for liniments
EMBROCATION
two special label instructions for liniments
FOR EXTERNAL USE ONLY
DO NOT APPLY ON BROKEN SKIN
It is an ethereal solution that contains pyroxillin and alcohol
COLLODION
. Pyroxillin is made up of ____ and ____
NITRIC ACID
SULFURIC ACID
It is Useful in holding the edges of an incised wound together
COLLODION (FILM)
Collodion has a disadvantage of being ____
NON FLEXIBLE
Flexible collodion has 2% of ____ and 3% of ____
CAMPHOR
CASTOR OIL
Collodion used as keratolytic
SALICYLIC ACID COLLODION
Are viscous solutions or mixtures of medicinal substances in NOT LESS THAN 50% by weight of GLYCERIN
GLYCERITE
A glycerite that is used as an astringent
TANNIC ACID GLYCERITE
Toothache drops contains ____ and mixtures of ____ with __ or___
CLOVE OIL
PHENOL
CAMPHOR
CREOSOTE
What is the use of starch glycerites
TOPICAL PROTECTIVE
recommended alcohol intake for OTC products
Under 6 years of age
0.5%
recommended alcohol intake for OTC products
6-12 years old
5%
recommended alcohol intake for OTC products
Over 12 years old
10%
useful hydroalcoholic solvent in various pharmaceutical processes and preparations
DILUTED ALCOHOL
- used as rubefacient and soothing rub
- vehicle for topical prodcuts
isopropyl rubbing alcohol
- viscous liquid
- miscible with water and alcohol
- useful as solvent and is frequently substitued for glycerin
PROPYLENE GLYCOL
- concentrated or nearly saturated aqueous solution of sugar
- a self-preserved solution with a minmal tendency to undergo crystallization
SYRUP NF
METHODS OF PREPARING SYRUP
- w/ heat
- agitation w/o heat
- addition of sucrose
- percolation
METHODS OF PREPARATION OF ELIXIRS
- simple solution w/ agitation
- admixture of 2 or more liquid ing.
METHODS OF PREPARATION OF SPIRITS
- distillation
- by maceration
- by chemical reaction
- simple soln
spirits contain how many % of alcohol
50% - 90%
METHODS OF PREPARATION FOR AROMATIC WATER
- distillatio
- solution method
METHODS OF PREPARATION FOR TINCTURE
- extraction
- simple solution
fluid extract is prepared by
percolation
- alcoholic oleaginous solution or emulsion of various medical substances** intended for external application** to the skin, generally w/ rubbing
LINIMENTS / embrocations
soluble gun cotton, collodion cotton
pyroxillin
collodions are applied to the skin with
fine camel’s hair brush or glass applicator
- used as medicinal agent or as an aid in dissolving other drugs in water or alcohol
GLYCERITES
preparations that has the fastest absorption
parenteral preparations
solid vs liquid
which has faster absorption
liquid
solutions that has insoluble particles (powder)
suspensions
to be called a solution, powder should be ____
dissolved
added to reduce the amount of alcohol required
glycols
glycerin
it is the process in which water is boiled until it evaporates and condenses, leaving behind impurities with different boiling points
DISTILLATION
ion exchange method is referred to as
demineralized or deionized water
ADVANTAGES OF ORAL SOLUTION
homogenous
easier to swallow
faster onset of action
DISADVANTAGES OF ORAL SOLUTION
bulky
degarde more rapidly
more likely to interact with constituents
recommended adult dose of oral colonic lavage solution
4L
the sugar that is most frequently employed in syrups
sucrose
materials converted to glucose in the body
glycogenetic
- prepared by dissolving 85g of sucrose in enough purified water to make 100ml of syrup (85% w/v, 65% w/w)
- low solvent capacity
- minimal tendency to undergo crystallization
- self preserving
SIMPLE SYRUP
- aid in sleeping
- benadril
dipenhydramine elixir
primary solvents of elixir
alcohol & water
adjunct solvents in elixir
glycerin & PEG
non medicated elixirs are used as
diluent
most topical solutions & tinctures are prepared by
simple dissolving
tincture for arthritis, irritable bowel syndrome
BELLADONNA TINCTURE
cause precipitation of inactive constituent of tinctures
aging
the process of redistillation two or more times until the distillate becomes clear
COHOBATION
TRUE OR FALSE
gargle can be a mouthwash
true
TRUE OR FALSE
mouthwash can be a gargle
FALSE
moutwash cannot be a gargle
more on cosmetically prepared rather than therapeutic
mouthwash
glycerite that is topical protective
STARCH GLYCERITE
temporary relief of tootaches
tootache drops
FACTORS AFFECTING SOLUBILITY OF SOLUTION
- temperature
- chemical & physical properties
- pressure
- pH
- state of subdivision
- physical agitation
SPIRITS
distillation: BRANDY
35 - 60%
SPIRITS
distillation: WHISKY
47 - 53%
liniment with rubefacient property
alcoholic liniment
liniment that requires massage
oily liniments