T6: Acute Kidney Injury Flashcards
Acute Kidney Injury (AKI)
rapid (sudden) loss of renal function due to damage to the kidneys; formerly called acute renal failure
AKI is accompanied by a rise in
serum creatinine level and/or a reduction in urine output
mean arterial pressure for the kidney
60
GFR tells you
how effective the kidney is
azotemia
an accumulation of nitrogenous waste products [urea nitrogen, creatinine] in the blood
pre-renal acute kidney injury
factors that reduce systemic circulation causing reduction in renal blood flow
pre-renal causes
*Severe dehydration,
*heart failure,
*↓ CO
HINT HINT: Prerenal azotemia results in
üreduction in the excretion of sodium (less than 20 mEq/L), increased salt and water retention, and decreased urine output.
intrarenal acute kidney injury
causes include conditions that cause direct damage to kidney tissue
intrarenal acute kidney injury causes
kindey stones, kidney cancer/tumors, DRUGS (nephrotoxic), bullet, crushed in accident, ect trauma
Postrenal acute kidney injury
occurs with urinary tract obstructions that affect the kidneys bilaterally
Postrenal acute kidney injury causes
*Benign prostatic hyperplasia (BPH)
*Prostate cancer
*Calculi
*Trauma
*Extrarenal tumors
*Bilateral ureteral obstruction
HINT HINT: what is the rifle classification
used to describe the stages of AKI
RIFLE classification
Risk (R)
Injury (I)
Failure (F)
Loss (L)
End-stage renal disease (E).
what labs do we use to check for kidney failure
BUN and CRE
oliguria UO amount
less than 400mL/day
oliguric phase occurs within
1-7 days after injury