T11: Hodgkin & Non-Hodgkin Lymphoma Flashcards
lymphoma
malignant neoplasms originating in bone marrow and lymphatic structures; results in proliferation of lymphocytes
Hodgkin’s Lymphoma
Malignant condition with proliferation of abnormal giant, multinucleated cells; HINT HINT REED-STERNBERG CELLS, located in lymph nodes
clinical manifestations Hodgkin’s Lymphoma
o Nodes remain movable and non-tender
o Painless unless nodes exert pressure on adjacent nerves
- Enlargement of cervical, axillary, or inguinal lymph nodes
o Weight loss (how much and over what period of time)
- Fatigue and weakness
- Fever and chills (FEVER OF UNKNOWN ORIGIN)
- Tachycardia
- Night sweats
location of Malignant condition with proliferation of abnormal giant, multinucleated cells; HINT HINT REED-STERNBERG CELLS, located in lymph nodes
o DISESASE BEGINS ABOVE THE DIAPHRAGM; remains in lymph nodes for variable amount of time
o BELOW THE DIAPHRAGM; frequently spreads to extra lymphoid sites
Second most common location of hodgkins lymphoma is
MEDIASTINAL NODE MASS
B symptoms
- Fever > 100.4 F (380 C)
· Low grade - Drenching night sweats
- Weight loss exceeding 10% in 6 months
MEDIASTINAL NODE INVOLVEMENT is evident with
Cough, dyspnea, stridor, dysphagia
intervention for hodgkins lymphoma
· Chemo, radiation, radiation (take out lymph node or splenectomy)
Secondary cancers can develop (malignancies): occur 10 years after treatment of Hodgkin’s lymphoma
- Lung cancer
- Breast cancer
Skin in radiation field needs ATTENTION
MILD SOAP AND WATER; PAT DRY, no perfume or Vaseline
Non-Hodgkin’s Lymphoma
Heterogeneous group of malignant neoplasms of immune system affecting all ages; primarily B-, T-, or NK- cell origin; widespread lymph node involvement
clinical manifestations of Non-Hodgkin’s Lymphoma
o Painless lymph node enlargement
(Primary clinical manifestation)
o Patients with high-grade lymphomas
-Lymphadenopathy
- B symptoms
· Fever
· Night sweats
· Weight loss
Prognosis for NHL generally is
not as good as that for Hodgkin’s lymphoma
treatment for NHL
-Chemotherapy
- Radiation therapy
o Hematopoietic stem cell transplant (HSCT)
o Rituximab (Rituxan): binds to cells an causes lysis and cell death
radiation precautions
The nurse should wear a lead shielding apron and should always face the radiation source. The nurse should never turn his/her back toward the radiation source.
The client should be assigned to a private room with a private bath.
Visitors should be advised to stay at least 6 feet from the radiation source at all times
The correct answer is: Always face the radiation source., Assign the client to a private room with a private bath., Encourage visitors to stay at least 6 feet from the client.