T1 L7: Salt and water reabsorption Flashcards
1
Q
What does apical mean?
A
Facing the lumen
2
Q
What does basolateral mean?
A
Facing the basement membrane
3
Q
What is the role of aldosterone in absorption?
A
Upregulates Na+ absorption by the stimulation of the Na+/K+ ATPase
4
Q
What role do glucocorticosteroids and somatostatin have in absorption?
A
They increase water and NaCl absorption by upregulation of the Na+/K+ ATPase pump
5
Q
What is the gene that causes Cystic fibrosis?
A
Deletion of the CFTR channel causing a malfunctioning Cl- transporter
6
Q
What is the mechanism behind lactose intolerance?
A
Deficiency in lactase so lactose is not digested properly. This causes a osmotic gradient and therefore diarrhoea
