T Cell Function-Lecture 10/12/21 Flashcards
1
Q
5 subsets of helper T cells
A
- Th1
- Th2
- Th17
- Tfh
- Treg
2
Q
Signature cytokines of Th1
A
IFN-gamma
3
Q
Signature cytokines of Th2
A
IL-4 and IL-5
4
Q
Signature cytokine of Th17
A
IL-17
5
Q
Signature cytokine of Tfh
A
IL-21
6
Q
Signature cytokine of Treg
A
IL-10, TGF-B
7
Q
What Th1 acts on
A
Macrophages, NK cells, CD8 T cells
8
Q
What Th2 acts on
A
Eosinophils, basophils, mast cells
9
Q
What Th17 acts on
A
Neutrophils and epithelial cells
10
Q
What Tfh acts on
A
Naive B cells
11
Q
Polarized response
A
In response to a particular pathogen, one type of helper T cell is made more than others
12
Q
Th1 function
A
Viral and intracellular bacterial infection
13
Q
Th2 function
A
Parasites and allergy
14
Q
TH17 function
A
Fungi and extra cellular bacteria
15
Q
IL-12
A
Cytokine that is released when DC recognizes a virus, stimulates Th1
