Systems lecture (bone lecture) Flashcards
Function
Provides support and protection and movement
Hemopoiesis
Blood cell production in bone marrow ( located in spongy bone)
Mineral and energy reserves
Calcium for muscle contractions, blood clotting and nerve impuls transmission
Phosphate for ATP
Bone classification
Long: Femur, humerus, MC, MT, clavicle, tibia/fibula, radius/ulna
Short: Tarsal, Carpal
Irregular: vertebrae, hip, mandible, coccyx
Flat: bones of skull, sternum, ribs, scapula
Types of bone cells
Osteoprogenitor cells (stem cells)
Osteoblasts (produce new bone)
Osteocytes (mature bone cells)
Osteoclasts (break down bone)
Layers of bone
Periosteum
Compact bone
Spongy bone
Periosteum
Structural unit of compact bone
Osteons (house VANs within central canals)
Divits in osteons are called lacuna and house osteocytes
Bone development
1) Fetal hyaline cartilage model develops
2) Cartilage calficies and bone collar forms around diaphysis
3) Primary ossification center forms in diaphysis
4) Secondary ossification form in epiphyses
5) Bone replaces caritlage ecept the articular and epiphyseal cartilage
6) Epiphyseal plates ossify and form epihyseal lines
Hormonal effect on bone
GH stimulates formation of somatomedin by liver, which influences the growth of cartilage in the epiphyseal plate
Thyroid hormones regulate and maintain normal activity at epiphyseal plates until puberty