Systemic Skin Disorders Flashcards
WHat are the traits of Dermatomyositis?
Skin lesions: Heliotrope (Purple discoloration)
Gottron’s Sign (red, raised dots on fingers)
Erethema on ext surface
What is the Tx of Dermatomyositis?
Steroids, immunosupressants, sunscreen
Waht are the traits of lupus?
Malar(butterfly) Rash, Discoid Rash, Photosensitivity,
What are the drugs that can cause subacute cutaneous LE?
HCTZ, CCBs, ACEi, Terbinafine
What is the Tx of Cutaneous lupus?
Topical or intralesional corticosteroids
What are the traits of Scleroderma?
CREST Syndrome
Skin thickening/fibrosis of hands
What are the Components of CREST syndrome?
CREST
Calcinosis- Ca dept in skin
Raynaud’s- spasm of BV
Esophageal DF- Acid Reflux and Decrease in motility
Sclerodactyly- Finger and handskin gets tight and thick
Telangectasias- dilation of cap => red marks on skin
What are the skin features of Localized scleroderma?
Morphea- raised white scar w/ lilac ring. Tx w/ steroids
Linear Scleroderma- bands crossing joint lines
En Coup De Sabre- on face
What is the appearance of Reiter’s syndrome?
Reactive Arthritis- Arthritis
Balanitis. Urethra, etc
What are the cutaneous manifestations of T cell Lymphoma?
Vascular skin changes w/ darker pigmentation. Psoriatic plaques
What are the cutaneous manifestations of Paget’s disease of breast? of bone has no skin lesions…
Non-healing lesion of the breast, esp around the areola
What are the cutaneous skin lesions of kaposi’s Sarcoma?
HHV8- Dark spots, can look like small bruises
What is Sweet’s Syndrome?
Looks like Herpes Zoster
Acute Febrile Neutrophilic Dermatosis
What are the cutaneous manifestations of Hypothyroidism?
Myxedema- Pretibial area and face
Triad: Edematous eyelids, swollen lower lip, and droopy facial appearance
What are the cutaneous changes with DM?
Acanthosis Nigricans
Diabetic Dermopathy
Necrobiosis Lipoidica Diabeticorum
Granuloma Annulare
What are the cutaneous changes of Addison’s disease?
Hyperpigmentation, vitelligo (anorexia, weakness, fatigue)
What are the cutaneous traits of Cushing’s Disease?
Striae, Buffalo hump, trunkal obesity
What are the cutaneous manifestations of Gout?
Precipitates when temp drops at night in lower ext
-red swollen toe joint with erythema
What are the traits of pseudogout?
Calcium Pyrophosphate Deposition in joints
What is the cutaneous appearance of RA?
Rheumatoid nodules, livedo reticularis(dark patch)
What is the cutaneous appearance of Psoriatic Arthritis?
Nail dystrophy
Neg Rheumatoid factor
Plaques- PUVA + sun exposure
What is the cutaneous appearance of Sarcoidosis?
Lupus Pernio. Telangectasias on face
Erythema Nodosum
Uveitis
What are the traits of Peutz-Jegher’s Syndrome?
Mucocutaneous lesions (hyperpigmentation in the mouth/hands and feet) -Hamartomatous polyps in GI tract
What are the traits of Osler-WeberRendu Syndrome?
Mucocutaneous telangectasias
