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Dermatology > Benign Skin Tumors > Flashcards

Benign Skin Tumors Flashcards

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Dermatology Board Prep flashcards
1
Q

What are the traits of Seborrheic Keratoses?

A

Round, flat, coin like, waxy plaques. Pigmented or non

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2
Q

What is the Tx of Seborrheic Keratoses?

A 
Surgery
Chemical Peeling Agents
Electrocautery
Cryotherapy
Only if bothersome
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3
Q

What is the Lesser Trelat Sign?

A

Numerous SK indicating visceral malignancy

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4
Q

What is a Fibroepithelial Polyp-Acrochordon?

A

Fibrovascular core covered by benign squamous epithelium (skin tags)

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5
Q

List the types of Epithelial Cysts?

A

Epidermal Inclusion cysts
Pilar or trichilemmal cysts
Dermoid Cysts
Steatocystoma multiplex

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6
Q

What are the traits of Epidermal Inclusion cysts?

A

Filled loosly w/ Keratin

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7
Q

What are the traits of Trichilemmal cysts?

A

Filled tightly w/ keratin

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8
Q

What are the traits of Dermal cysts?

A

Subcutaneous nodule at birth on lateral aspect of upper eyelid

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9
Q

What are the traits of Steatocystoma multiplex?

A

AD mutation in Keratin 17

Sternal, axillae, groin

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10
Q

What are the traits of Trichilemmoma and cowden’s disease?

A

Solitary

Cowden’s: AD, mutation of tumor supressor PTEN

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11
Q

What are the traits of Pilomatrixoma?

A

Solitary firm nodule on head, upper limbs, neck, trunk

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12
Q

What are the traits of Birt-Hogg-Dube Syndrome?

A

Mutation of BHD gene on chromosome17
Multiple microfolliculomas
Fibrofolliculoma**
Trichodiscoma**

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13
Q

What are the traits of Nevus Sebaceous?

A

Head/neck, scalp.

Benign but 2^ tumor can arise within

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14
Q

What are the traits of Sebaceous Hyperplaia?

A

Face of older adults
Mis-dx as BCC
Yellowish dome shaped papules

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15
Q

What are the Traits of Sebaceous Adenoma?

A

Muir-Torre Syndrome

Face and scalp of older people

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16
Q

What are the traits of Muir-Torre Syndrome?

A

Related to HNPCC (DNA mismatch repair) AD

MSH2 gene mutated

17
Q

What are the findings in MTS?

A

Sebaceous tumors

GI, Bladder, Endometrial, Breast Cancer

18
Q

How is MTS Diagnosed?

A

Immunostaining for mismatch repair Ez

Followup w/ genetic sequencing

19
Q

What are the traits of Cylindroma?

A 
Pink/red nodule
Brook-Spiegler synd
F:M 9:1
Turban tumor
Jigsaw puzzle epithelial cells
20
Q

What are the traits of Xanthomas?

A

Aggregate of Histiocytes w/ cytoplasmic lipid

21
Q

What are the 5 types of Xanthomas?

A

Eruptive, Tendinous, Tuberous, Planar, Disseminated

22
Q

What are the traits of Xanthogranuloma?

A

Yellow/Brown/orange papule or nodule
Accoc w/ CML and NF
Regresses

23
Q

What are the traits of Reticulohistiocytoma?

A

Solitary or multicentric reticulohistiocytosis

Ground glass histiocytes

24
Q

What are the traits of Langerhans Cell Histiocytosis?

A

Proliferation of Lang cell type histiocytes in tissue

25
Q

What is the Most aggressive form of LCH?

A

Acute Generalized LCH

High M and M

26
Q

What are the Traits of Lipomas?

A

Most common connective tissue tumor

Benign. Excision is curative

27
Q

What are the traits of Traumatic neuromas?

A

Peripheral n severed and doesn’t heal

Disorderly proliferation

28
Q

What are the traits of Morton’s neuromas?

A

Pain of sole of foot
Region of metatarsal heads
Walking makes it worse

29
Q

What are the traits of Mucosal neuromas?

A

MEN 2b
Need genetic testing and Thyroid imaging
Multiple and clustered around the mouth

30
Q

What are the traits of Palisaded Encapsulated Neuroma?

A

Solitary painless nodule

Face most common site

31
Q

What are the traits of a Schwannoma?

A

Hyalinized Vessels
Antoni A and B
Prominent BV

32
Q

What are the traits of Neurofibroma?

A

Solitary Polypoid or nodular lesion

Plexiform = NF-1

33
Q

What are the traits of Giant cell tumors of the Tendon sheathe?

A

Hands/Feet/wrists/knees

Nodular Tenosynovitis

34
Q

What are the traits of Ganglion cysts?

A

Myxoid Degen of joint capsule or tendon sheathe
2^ to injury or overuse
Cystic space lined w/ histiocytes and gran tissue
Mucin pockets

35
Q

What are the traits of Superficial Firomatosis?

A

Hand- Dupuytren contrcture
Penile
Plantar
Not assoc w/ Beta-catenin mutations

Dermatology (12 decks)

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