Intro to Derm

Question 1

What items are needed for an effective total body skin exam?

Answer 1

Lighting, Undressed patient in gown, Privacy, RULER, Magnifying glass, Open mind, CHAPERONE

Question 2

What are the Indications of a Total body Skin exam?

Answer 2

Hx of Skin cancer
Inc risk for melanoma or malignancy
New rash or lesion of concern
F/U for extensive skin lesions

Question 3

What are the types of Flat primary skin lesions.

Answer 3

Macule 1cm

Question 4

What are the types of Raised, solid lesions?

Answer 4

Papule 1cm
Tumor>2cm
Plaque>1 cm and flat topped

Question 5

What are the types of Raised, fluid filled lesions?

Answer 5

Vesicles: Clear fluid 1cm
Pustule: White Fluid, filled w/ pus

Question 6

What is a Wheal?

Answer 6

Round or flat topped edematous and erythematic, shape subject to change

Question 7

What is a telangectasia?

Answer 7

Enlarged Superficial BV

Question 8

What is an erosion?

Answer 8

Loss of epidermis, depression in skin, heals without scar

Question 9

What is a scale?

Answer 9

Flake or plates of skin

Question 10

What is a crust?

Answer 10

Dried plasma or exudate

Question 11

What is an ulcer?

Answer 11

Loss of epidermis, part/complete dermis, heals with scar

Question 12

What is a Excoriation?

Answer 12

Traumatized or Abraided skin

Question 13

What is a Petichiae vs Purpura vs Ecchymoses?

Answer 13

Petichiae 1-2mm
Purpura 3 mm
Ecchymoses >1cm

Question 14

What are the traits of Tinea Versicolor?

Answer 14

Malessezia furfur

Tx Ketoconazole shampoo

Question 15

What is the MOA of Topical Steroids?

Answer 15

Inhibits NF-kB, supresses B and TC function. no cytokine transcription. Demarginalization of neutrophils, chronic immunosupression

Question 16

What is the Purpose of Topical Steroids?

Answer 16

Inflammation

Burn and Pruritic Relief

Question 17

What are the SA of Topical Steroids?

Answer 17

Skin atrophy, Telangectasias, Striae, Acne, Steroid Rosacia, Hypopigmentation, Systemic

Question 18

What is the use of Super high potency topical steroids?

Answer 18

Severe Dermatoses. Non-thin skin areas

Question 19

What is the use of Med to high potency topical steroids?

Answer 19

Mild to moderate nonfacial and non interiginous areas

Question 20

What is the use of low potency topical steroids?

Answer 20

Large areas and on thinner skin. OK on Face, eyelid, genital, intriginous areas
1-2 wk intervals

Question 21

What is the order of Moistness of Vehicles?

Answer 21

Solution 
Spray
Gel
Foam
Oil
Ointment
Lotion
Cream ###

Question 22

What are the Tx of Acne Vulgaris?

Answer 22

Benzoyl Peroxide
Topical Abtx
Topical Retinoids
Oral Abtx
Oral retinoids

Question 23

What is the MOA of Oral Antihistamines?

Answer 23

Blocks histamine. Hist vasodilates and makes vessels more permiable. affects sleep. Inc Gastric Acid Release.
Drys out everything. Wobbly

Question 24

What are the 1st gen H1 Antagonists?

Answer 24

SEDATING
Diphenhydramine
Hydroxyzine
Chlorphenirimine

Question 25

What are the 2nd gen H1 Antagonists?

Answer 25

Ceterizine Loratidine Fexofenidine (itch)

Question 26

What are the H2 antagonists?

Answer 26

Ranitidine(-idine) GERD not DERM

Question 27

What are the Labs to get to Dx Lupus?

Answer 27

``` Anti-dsDNA Anti-Smith Antihistone Anticardiolipin Abs Complement Levels ```

Question 28

What are the most common causes of Death in Lupus?

Answer 28

1) CV 2) Infection 3) Renal Disease

Question 29

What is the Mnemonic for other signs of lupus?

Answer 29

``` RASH OR PAIN Rash Arthritis Soft tissues/serositis Hematologic Dis Oral ulcers Renal Dis Photosensitivity ANA Ab Immunosupressants Neurologic Disorders ```

Question 30

What are the causes of Drug induced lupus?

Answer 30

``` Sulfa Hydralazine INH, Procainamide Phenytoin Etancercept ```

Question 31

What causes Miscarriage in Lupus Patients?

Answer 31

Antiphospholipid Ab syndrome

Question 32

What is the Tx of Lupus?

Answer 32

NSAIDs | Steroids, Immunosupressants, hydroxychloroquine

Question 33

What Ez do Allylamines inhibit?

Answer 33

Squalene Epoxidase

Question 34

What Ez do Azole Antifungals inhibit?

Answer 34

14-a-demethylase